Intravitreal ganciclovir treatment in progressive outer retinal necrosis

American Journal of Ophthalmology
E Pérez-BlázquezM Montero

Abstract

To report two patients with progressive outer retinal necrosis, which is presumed to be caused by the varicella-zoster virus in patients with acquired immunodeficiency syndrome (AIDS). Case report. The patients were treated with intravenous foscarnet, 60 mg per kg of body weight three times per week, without response. Remission of retinal necrosis occurred with the commencement of intravitreal ganciclovir treatment, 400 mg two times per week. Laser photocoagulation was performed in both cases. Neither patient developed retinal detachment. Intravitreal ganciclovir treatment combined with systemic antiviral agent therapy in patients with progressive outer retinal necrosis may delay progress of the disease. Early photocoagulation may prevent the development of retinal detachment if retinal necrosis is controlled.

References

Aug 15, 1991·American Journal of Ophthalmology·T P MargolisJ J O'Donnell
Apr 1, 1995·American Journal of Ophthalmology·M K PinnolisB Kemp

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Citations

Mar 15, 2003·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·G GrossH W Doerr
May 24, 2015·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Chien-Chi TsengHuan-Sheng Chen
Feb 7, 2007·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Philip D YinMary E Wright
Sep 1, 2016·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Sanjeet K Shahi
Dec 5, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Robert H DworkinRichard J Whitley
Apr 26, 2003·The Pediatric Infectious Disease Journal·Kenneth W PurdyMargaret A Keller
Mar 26, 2005·International Ophthalmology Clinics·Ehud Zamir
Jun 4, 2005·Clinical & Experimental Ophthalmology·Weng T Ng, Patrick Versace
Mar 13, 2019·Clinical & Experimental Ophthalmology·Xia Ni WuOren Tomkins-Netzer
Jan 9, 2010·Retina·Beeran MeghparaDebra A Goldstein
Sep 28, 2002·The Journal of Infectious Diseases·John W Gnann
Jul 18, 2001·European Journal of Ophthalmology·E A Roig-MeloD V Alfaro
Jul 19, 2013·Postgraduate Medical Journal·Robert William WongEmmett T Cunningham
Mar 25, 2004·Journal français d'ophtalmologie·T H C TranP LeHoang

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