Intravoxel incoherent motion diffusion-weighted imaging for assessment of histologic grade of hepatocellular carcinoma: comparison of three methods for positioning region of interest

European Radiology
Yi WeiBin Song

Abstract

To prospectively compare the diagnostic performances of three methods of region of interest (ROI) placement for the measurements of intravoxel incoherent motion (IVIM) diffusion-weighted MR imaging in differentiating the histologic grade of hepatocellular carcinoma (HCC). Eighty-seven patients with 91 newly diagnosed HCCs were studied using IVIM imaging. Two attending radiologists separately identified the selection of tumour tissue for ROI positioning. Three different ROI positioning methods, namely the whole tumour volume (WTV) method, three-ROI method and one-section method, were used for the measurement. Kruskal-Wallis rank test or one-way ANOVA was used to compare the difference in IVIM parameters and ADC across the three different ROI positioning methods. Spearman correlation analysis was used to determine the correlation between each parameter and Edmondson-Steiner (E-S) grade. Receiver operating characteristics (ROC) curve analyses were performed to evaluate the diagnostic performance. For the ADC and ADCslow, the mean value measured by using the WTV method was significant higher than the one-section and three-ROI methods (all p < 0.01). For the ADCslow, the highest area under curve (AUC) with a value of 0.969 was obtai...Continue Reading

References

Aug 9, 2011·European Radiology·Doenja M J LambregtsRegina G H Beets-Tan
Aug 28, 2014·Journal of Cancer Research and Clinical Oncology·P FitzmorrisA K Singal
Dec 23, 2014·Radiology·Matthias BarralPhilippe Soyer
Jan 13, 2015·European Radiology·Lukas FilliAndreas Boss
Feb 6, 2015·CA: a Cancer Journal for Clinicians·Lindsey A TorreAhmedin Jemal
Feb 12, 2017·Hong Kong Medical Journal = Xianggang Yi Xue Za Zhi·K W MaC M Lo
Jul 9, 2017·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Colin M CourtVatche G Agopian

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Citations

Jun 17, 2020·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Mami Iima
Mar 17, 2019·European Radiology·Yi WeiBin Song
Sep 3, 2020·World Journal of Clinical Cases·Yun-Yun TaoXiao-Ming Zhang
Jan 24, 2020·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Minghui SongQueenie Chan
Jul 3, 2021·Journal of Clinical Medicine·Liberatore TramontanoValentina Brancato

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