PMID: 6987598Jan 1, 1980Paper

Intrinsic regulation of the condylar cartilage growth rate (author's transl)

Pathologie-biologie
J Stutzmann, A Petrovic

Abstract

The experimental results reported above, strongly suggest the existence of an intrinsic regulatory mechanism of the condylar cartilage growth rate. The cell density as such cannot account, at least not completely, for the findings. In other words, there must be a "negative feed-back signal" originating from the proximal part of the chondroblastic zone and exerting a restraining effect on the prechondroblastic multiplication rate. The concept of an intrinsic regulation of the condylar cartilage growth rate can help to explain the effects of some orthopaedic or orthodontic appliances as well as of a hormone, thyroxine. The earlier commencement of chondroblastic hypertrophy and the subsequent decrease in the prechondroblast restraining signal appear to be an important intermediary step in the growth-stimulating effect of the mandibular postural hyperpropulsor. The acceleration of the chondroblastic maturation rate is, in a similar way, an intermediary step for the growth-rate stimulating effect of thyroxine.

Related Concepts

Structure of Articular Cartilage
Mandibular Condyle
M Phase, Mitotic
Structure of Pterygoid Muscle
Recombinant Growth Hormone
Novothyral

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Lipidomics & Rhinovirus Infection

Lipidomics can be used to examine the lipid species involved with pathogenic conditions, such as viral associated inflammation. Discovered the latest research on Lipidomics & Rhinovirus Infection.

Spatio-Temporal Regulation of DNA Repair

DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Torsion Dystonia

Torsion dystonia is a movement disorder characterized by loss of control of voluntary movements appearing as sustained muscle contractions and/or abnormal postures. Here is the latest research.

Archaeal RNA Polymerase

Archaeal RNA polymerases are most similar to eukaryotic RNA polymerase II but require the support of only two archaeal general transcription factors, TBP (TATA-box binding protein) and TFB (archaeal homologue of the eukaryotic general transcription factor TFIIB) to initiate basal transcription. Here is the latest research on archaeal RNA polymerases.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.

Related Papers

American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics
J Stutzmann, A G Petrovic
The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society
Q LiuC Qin
© 2021 Meta ULC. All rights reserved