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Intrinsically unstructured proteins and their functions

Nature Reviews. Molecular Cell Biology

Mar 2, 2005

H J Dyson, P E Wright

Abstract

Many gene sequences in eukaryotic genomes encode entire proteins or large segments of proteins that lack a well-structured three-dimensional fold. Disordered regions can be highly conserved between species in both composition and sequence and, contrary to the traditional view that prote...read more

Mentioned in this Paper

Genome
Post-Translational Protein Processing
Tertiary Protein Structure
Protein Function
Plasma Protein Binding Capacity
Intrinsically Disordered Proteins
Protein p53
Nucleolar Proteins
CREB-binding protein
Nucleic Acids
2
1
1801
4
Paper Details
References
  • References120
  • Citations1698
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  • References120
  • Citations1698
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Intrinsically unstructured proteins and their functions

Nature Reviews. Molecular Cell Biology

Mar 2, 2005

H J Dyson, P E Wright

PMID: 15738986

DOI: 10.1038/nrm1589

Abstract

Many gene sequences in eukaryotic genomes encode entire proteins or large segments of proteins that lack a well-structured three-dimensional fold. Disordered regions can be highly conserved between species in both composition and sequence and, contrary to the traditional view that prote...read more

Mentioned in this Paper

Genome
Post-Translational Protein Processing
Tertiary Protein Structure
Protein Function
Plasma Protein Binding Capacity
Intrinsically Disordered Proteins
Protein p53
Nucleolar Proteins
CREB-binding protein
Nucleic Acids
2
1
1801
4

Similar Papers Found In These Feeds

Nucleolar Dynamics

The nucleolus is the site of ribosome biogenesis, making ribosomal subunits from proteins and ribosomal RNA. Discover the latest research on nucleolar dynamics here.

Protein Function Prediction

Protein function prediction methods are techniques that bioinformatics researchers use to assign biological or biochemical roles to proteins. Discover the latest research on protein function prediction here.

Related Papers

Trends in Biochemical Sciences

Intrinsically unstructured proteins

Trends in Biochemical SciencesOctober 9, 2002
Peter Tompa
Journal of Molecular Graphics & Modelling

Intrinsically disordered protein

Journal of Molecular Graphics & ModellingMay 31, 2001
A Keith DunkerZoran Obradović
Paper Details
References
  • References120
  • Citations1698
12345...
  • References120
  • Citations1698
12345...
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