Introducing a novel in vivo method to access visual performance during dewetting process of contact lens surface.

Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association
Oliver KolbeWolfgang Sickenberger

Abstract

To introduce a novel in vivo method (Visual Acuity Dry Up; VADU) for testing the visual performance during the dewetting of the pre-lens tear film on a contact lens (CL). Thirty-nine subjects were fitted with daily disposable CL (Nelfilcon A). Visual performance and dewetting characteristics of the pre-lens tear film were simultaneously assessed using a modified multifunctional topographer (Keratograph 5 M, OCULUS Optikgeräte GmbH, Wetzlar, GERMANY) and the Non-Invasive Keratograph Dry-Up Time (NIKDUT) method. Measures were taken after five minutes and eight hours of CL wear and included the Visual Acuity Dry-Up Time (VADUT; time between last blink and visual breakdown) and the Visual Acuity Dry-Up Area (VADUA; dewetted CL area at visual breakdown) at one (VA+0.1logMAR), two (VA+0.2logMAR) and three (VA+0.3logMAR) log units below maximal visual acuity (VA). Participants lost one, two or three log units of VA after 13.1 ± 17.4 s, 20.83 ± 21.81, 34.67 ± 29.11 (VADUT), corresponding to a dewetted CL area of 4.82 ± 6.64 mm², 9.5 ± 8.26 and 13.0 ± 8.68 (VADUA), respectively. Differences in VADUT und VADUA for all visual requirements were significant (all p < 0.05). VADUT and VADUA did not vary with CL wear duration (all p > 0.05). A...Continue Reading

References

Mar 1, 1992·The British Journal of Ophthalmology·G Rieger
Nov 1, 1991·Optometry and Vision Science : Official Publication of the American Academy of Optometry·S PatelL Hunter
Feb 25, 1993·The New England Journal of Medicine·K Tsubota, K Nakamori
Mar 22, 2000·Psychiatry Research·G BarbatoF Rinaldi
Feb 1, 2002·Current Eye Research·S TongeB Tighe
Nov 1, 2002·Klinische Monatsblätter für Augenheilkunde·Wolfgang Wesemann
Apr 27, 2005·Survey of Ophthalmology·Clayton BlehmRichard W Yee
Jan 1, 1997·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·C AlbarránJ M Artigas
Jan 16, 2007·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Michael Bach
Oct 17, 2007·Environmental Science & Technology·Congrong HeLen Taplin
Jan 22, 2009·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Nikole L HimebaughJenni A Wilkinson
Feb 13, 2010·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·James S WolffsohnAshock Chowdhury
Apr 13, 2011·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Mark Rosenfield
Mar 30, 2013·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Joan K PortelloChristina A Chu
Jun 19, 2013·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Masakazu HirotaShinya Yamamoto
Jul 10, 2013·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Katie EdwardsFiona Stapleton
Sep 13, 2013·Environmental Health : a Global Access Science Source·Nithya ElangoJeyanthi Govindasamy Poornima
Jan 15, 2014·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Christina A ChuJoan K Portello
May 17, 2014·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Peiyi KoDavid M Rempel
Oct 4, 2014·Langmuir : the ACS Journal of Surfaces and Colloids·M Saad BhamlaGerald G Fuller
Jul 21, 2015·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Michel GuillonRenée Garofalo
Aug 21, 2015·MMWR. Morbidity and Mortality Weekly Report·Jennifer R CopeMichael J Beach
Oct 31, 2015·Investigative Ophthalmology & Visual Science·Marc ArgilésMargarita Rodríguez
May 28, 2016·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Dorota H Szczesna-IskanderD Robert Iskander
Feb 9, 2017·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Raied FagehiAlan Tomlinson
Aug 30, 2017·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Sebastian Marx, Wolfgang Sickenberger
Jul 3, 2018·BMJ Open Ophthalmology·Amy L Sheppard, James S Wolffsohn

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Citations

Oct 29, 2020·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Erol Havuz, Onur Gokmen
Mar 30, 2021·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Mark WillcoxLyndon Jones
Aug 11, 2021·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Carlos Carpena-TorresGonzalo Carracedo

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