Introducing a static receptor to compete with a dynamic combinatorial library in template binding

Organic & Biomolecular Chemistry
Filip UlatowskiJanusz Jurczak


We show herein that establishing a competition between a static receptor and components of dynamic combinatorial libraries to bind an appropriately selected template can be used to determine association constants by HPLC analysis after freezing of the equilibrium.


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High Pressure Liquid Chromatography Procedure
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