Introducing a static receptor to compete with a dynamic combinatorial library in template binding

Organic & Biomolecular Chemistry
Filip UlatowskiJanusz Jurczak

Abstract

We show herein that establishing a competition between a static receptor and components of dynamic combinatorial libraries to bind an appropriately selected template can be used to determine association constants by HPLC analysis after freezing of the equilibrium.

References

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Citations

Apr 12, 2017·Journal of the American Chemical Society·Dávid KomáromySijbren Otto

Related Concepts

High Pressure Liquid Chromatography Procedure
Synthetic Peptide Combinatorial Library
Receptor
Binding (Molecular Function)

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