PMID: 9180796Nov 1, 1996Paper

Introduction of a donor exposure reduction programme for multiple-transfused very-low-birth-weight infants

South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
G F KirstenA R Bird

Abstract

To conduct an audit of the frequency of red cell concentrate transfusions (RCCTs) in infants of different weight categories, the donor exposure rate (DER), in these transfused infants and the volume of blood wasted during each transfusion, and to identify from this baseline information specific categories of infants who would benefit from the introduction of a limited donor exposure programme (LDEP). Neonatal wards and neonatal intensive care unit (NICU), Tygerberg Hospital, Western Cape. A prospective descriptive study and comparison with a historic control group. Information on the birth weight, age at the time of each RCCT and number of blood donors to whom an infant was exposed were collected post factum for all infants admitted to the neonatal wards and NICU between May 1993 and May 1994. During this time, the red blood cell concentrate was supplied as single paediatric bags (180 ml) transfused within 14 days of donation. An LDEP was introduced in February 1995. With this system, red blood cells were supplied as triple packs: a main unit of 250 ml with three empty satellite packs allowing up to three separate transfusions. These were assigned to a specific infant and were to be transfused within 21 days of donation. A seco...Continue Reading

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