Introduction of fixed-flow mode in the DexAide right ventricular assist device.

The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation
Diyar SaeedKiyotaka Fukamachi

Abstract

Although some continuous-flow left ventricular assist device algorithms have been created to respond to varying patient physiology, very little research has been conducted on control of right ventricular support in uni- or biventricular application. The purpose of this study was to develop and evaluate a simple and reliable fixed-flow algorithm for the DexAide right ventricular assist device (RVAD). This algorithm automatically adjusts speed to maintain a target flow while preventing ventricular suction when a requested target flow exceeds available tricuspid flow. Fixed-flow control mode was evaluated in 17 DexAide RVAD long-term bovine studies, with a duration ranging from 14 to 90 days (33 +/- 24 days). Targeted fixed-flow levels ranged from 4.0 to 6.5 liters/min. Data were monitored on an hourly basis. Pump-flow data were also recorded on a weekly basis to document the speed increment required to increase pump flow from 5 to 8 liters/min at 0.5-liter/min increments. The fixed-flow control mode was evaluated for a total duration of 5,283 hours without complications related to pump flow or left/right circulation imbalance. The pump speed varied between 2,000 and 3,220 rpm to maintain the flow constant at each target level. Th...Continue Reading

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Dec 13, 2005·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Kiyotaka FukamachiLeonard A R Golding
Dec 13, 2005·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Yoshio OotakiKiyotaka Fukamachi
Feb 1, 2006·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Heinrich SchimaGeorg Wieselthaler
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Jan 22, 2008·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Diyar SaeedKiyotaka Fukamachi

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Citations

Jul 9, 2011·Annals of Biomedical Engineering·Shaun D GregoryJohn F Fraser
Aug 14, 2012·Artificial Organs·Shaun David GregoryDaniel Timms
May 15, 2018·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Steven G ChopskiAmy L Throckmorton
Dec 2, 2020·The International Journal of Artificial Organs·Yuichiro KadoKiyotaka Fukamachi

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