Introduction to machine learning

Methods in Molecular Biology
Yalin Baştanlar, Mustafa Ozuysal


The machine learning field, which can be briefly defined as enabling computers make successful predictions using past experiences, has exhibited an impressive development recently with the help of the rapid increase in the storage capacity and processing power of computers. Together with many other disciplines, machine learning methods have been widely employed in bioinformatics. The difficulties and cost of biological analyses have led to the development of sophisticated machine learning approaches for this application area. In this chapter, we first review the fundamental concepts of machine learning such as feature assessment, unsupervised versus supervised learning and types of classification. Then, we point out the main issues of designing machine learning experiments and their performance evaluation. Finally, we introduce some supervised learning methods.


Sep 23, 2014·Protein Science : a Publication of the Protein Society·Panagiotis KatsonisOlivier Lichtarge
Feb 3, 2018·Biomedical Engineering Online·Robert Koprowski, Kenneth R Foster
Jul 11, 2019·Journal of Korean Neurosurgical Society·Kyoung Hyup NamIn Ho Han
Sep 1, 2018·American Journal of Clinical Pathology·Matthew W Rosenbaum, Jason M Baron
Nov 9, 2019·Environmental Science and Pollution Research International·Viviane Ribas PereiraAna Paula Alves Favareto
Aug 6, 2016·Molecular Informatics·Maolin WangJohann Gasteiger
Jun 3, 2020·Journal of the American Medical Informatics Association : JAMIA·Caitlin E CoombesKevin R Coombes
Oct 5, 2019·American Journal of Medical Quality : the Official Journal of the American College of Medical Quality·Samer EllahhamMecit Can Emre Simsekler
Oct 3, 2020·Molecular Genetics and Genomics : MGG·Lin ZhongQi Zhao
Dec 15, 2016·Journal of Experimental Botany·Anna WunderlingLaura Ragni
Apr 15, 2019·Cellular and Molecular Life Sciences : CMLS·E Joseph JordanRavi Radhakrishnan
Jul 1, 2020·Soa--chʻŏngsonyŏn Chŏngsin Ŭihak = Journal of Child & Adolescent Psychiatry·Da-Yea SongHee Jeong Yoo
Dec 31, 2019·Endocrinology and Metabolism·Hun Sung KimKun Ho Yoon
Jun 20, 2020·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Rudolf A WernerFrank M Bengel
Jun 21, 2019·International Journal of Environmental Research and Public Health·Bach Xuan TranRoger C M Ho

Related Concepts

Support Vector Machines
Knowledge Representation (Computer)
Bayesian Prediction
Discriminant Analysis

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Sexual Dimorphism in Neurodegeneration

There exist sex differences in neurodevelopmental and neurodegenerative disorders. For instance, multiple sclerosis is more common in women, whereas Parkinson’s disease is more common in men. Here is the latest research on sexual dimorphism in neurodegeneration

HLA Genetic Variation

HLA genetic variation has been found to confer risk for a wide variety of diseases. Identifying these associations and understanding their molecular mechanisms is ongoing and holds promise for the development of therapeutics. Find the latest research on HLA genetic variation here.

Super-resolution Microscopy

Super-resolution microscopy is the term commonly given to fluorescence microscopy techniques with resolutions that are not limited by the diffraction of light. Here are the latest discoveries pertaining to super-resolution microscopy.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells.

Brain Lower Grade Glioma

Low grade gliomas in the brain form from oligodendrocytes and astrocytes and are the slowest-growing glioma in adults. Discover the latest research on these brain tumors here.

CD4/CD8 Signaling

Cluster of differentiation 4 and 8 (CD8 and CD8) are glycoproteins founds on the surface of immune cells. Here is the latest research on their role in cell signaling pathways.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Related Papers

IEEE Reviews in Biomedical Engineering
Jianlin ChengPierre Baldi
Optometry and Vision Science : Official Publication of the American Academy of Optometry
Christopher Bowd, Michael H Goldbaum
Recent Patents on DNA & Gene Sequences
Irina Mohorianu, Vincent Moulton
Frontiers in Bioscience : a Journal and Virtual Library
David J MillerGeorge Kesidis
Methods in Molecular Biology
Itziar Frades, Rune Matthiesen
© 2020 Meta ULC. All rights reserved