Introduction to the Thematic Minireview Series: DNA double-strand break repair and pathway choice

The Journal of Biological Chemistry
Patrick Sung

Abstract

Environmental agents and reactive metabolites induce myriad chromosomal lesions that challenge the integrity of our genome. In particular, the DNA double-strand break (DSB) has the highest potential to cause the types of chromosome aberrations and rearrangements found in transformed and cancer cells. Several conserved pathways of DSB repair exist in eukaryotes, and these have been the subject of intense studies in recent years. In this Thematic Minireview Series, four leading research groups review recent progress in deciphering DSB repair mechanisms and the intricate regulatory network that helps determine the preferential engagement of one pathway over others.

References

Jan 5, 2016·Trends in Cancer·Nicholas A WillisRalph Scully
May 26, 2016·Nature Reviews. Cancer·Michael R Lieber
Dec 17, 2017·The Journal of Biological Chemistry·Nicholas R PannunzioMichael R Lieber
Feb 8, 2018·The Journal of Biological Chemistry·Joonyoung Her, Samuel F Bunting
Mar 14, 2018·The Journal of Biological Chemistry·Annahita Sallmyr, Alan E Tomkinson
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Apr 25, 2018·Cold Spring Harbor Symposia on Quantitative Biology·Weiran Feng, Maria Jasin

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Citations

Nov 20, 2018·Médecine sciences : M/S·Judith Miné-Hattab, Xavier Darzacq
Jan 25, 2019·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Lianying FangQiang Liu
May 2, 2020·Signal Transduction and Targeted Therapy·Rui-Xue Huang, Ping-Kun Zhou
Sep 2, 2020·International Journal of Molecular Sciences·Andrés Felipe LealAngela Johana Espejo-Mojica
Oct 31, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Roopa Thapar
Jul 14, 2019·Applied and Environmental Microbiology·Lei QiDao-Qiong Zheng
Jul 6, 2021·Frontiers in Genetics·Yasmeen NiaziAsta Försti

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