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Intron Lariat RNA Inhibits MicroRNA Biogenesis by Sequestering the Dicing Complex in Arabidopsis

PLoS Genetics

Nov 22, 2016

Ziwei LiBinglian Zheng

Abstract

Lariat RNAs formed as by-products of splicing are quickly degraded by the RNA debranching enzyme 1 (DBR1), leading to their turnover. Null dbr1 mutants in both animals and plants are embryo lethal, but the mechanism underlying the lethality remains unclear. Here we characterized a weak ...read more

Mentioned in this Paper

AGO1 gene
GAPDH gene
HSPA8 gene
DBR1 gene
Crossbreeding
Infertility Study
Co-Immunoprecipitation
Local
Oligonucleotide Primers
Metaplastic Cell Transformation
11
60
Paper Details
References
  • References37
  • Citations8
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Intron Lariat RNA Inhibits MicroRNA Biogenesis by Sequestering the Dicing Complex in Arabidopsis

PLoS Genetics

Nov 22, 2016

Ziwei LiBinglian Zheng

PMID: 27870853

DOI: 10.1371/journal.pgen.1006422

Abstract

Lariat RNAs formed as by-products of splicing are quickly degraded by the RNA debranching enzyme 1 (DBR1), leading to their turnover. Null dbr1 mutants in both animals and plants are embryo lethal, but the mechanism underlying the lethality remains unclear. Here we characterized a weak ...read more

Mentioned in this Paper

AGO1 gene
GAPDH gene
HSPA8 gene
DBR1 gene
Crossbreeding
Infertility Study
Co-Immunoprecipitation
Local
Oligonucleotide Primers
Metaplastic Cell Transformation
11
60

Similar Papers Found In These Feeds

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Paper Details
References
  • References37
  • Citations8
1234
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