Introns enable the polyomavirus middle and small T antigens to stimulate the growth of primary rat embryo fibroblasts

Gene
C AsselinM Bastin

Abstract

We constructed spliceable vectors that separately encode polyomavirus MT and ST. The addition of an intron enables MT to transform and to immortalize more efficiently and ST to transiently stimulate the growth of primary rat embryo fibroblasts.

References

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Citations

Nov 20, 1998·Molecular and Cellular Biology·K P MullaneB Schaffhausen

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