Abstract
Metagonimus yokogawai was found deeply invaded into the submucosa of the small intestine of mice (ICR) when they were immunosuppressed by prednisolone injection. Experimental groups consisted of control, fluke infection (1,800 metacercariae per mouse), and fluke infection plus immunosuppression. In fluke infection group, many worms were found sectioned in the intervillous space of the jejunum and ileum at 6 hrs, 12 hrs, and 1 day after infection, and pathological changes characterized by villous atrophy and crypt hyperplasia were observed. After 3 days, only a few worms were found in intestinal sections, and after 7 days, the pathological changes became minimal. No worm was found penetrated beyond the mucosal layer. On the other hand, in immunosuppressed mice, numerous worms were found sectioned in the duodenum and jejunum, irrespective of the infection period up to 14 days. Pathological changes of the mucosa were minimal until 3 days after infection, but at 5 days marked destruction of the mucosal layer was observed. At this time many flukes were found invaded deeply into the submucosa facing the muscular layer. Despite continuous immunosuppression, the mucosal damage was gradually recovered at 7-21 days post-infection. The re...Continue Reading
References
Dec 1, 1990·Parasitology·J M WastlingL H Chappell
Dec 1, 1990·Kisaengch'unghak chapchi. The Korean journal of parasitology·J Y Chai, S H Lee
Mar 1, 1990·Kisaengch'unghak chapchi. The Korean journal of parasitology·S J HongB S Seo
Dec 1, 1988·Journal of Korean Medical Science·J G ChiS H Lee
Dec 1, 1972·Experimental Parasitology·D G Colley
May 1, 1994·Transactions of the Royal Society of Tropical Medicine and Hygiene·D Jenkins, D Wakelin
Sep 1, 1988·Kisaengch'unghak chapchi. The Korean journal of parasitology·Yung Kyum Ahn, Yong Suk Ryang
Dec 1, 1985·Kisaengch'unghak chapchi. The Korean journal of parasitology·Young Kee JangSeung Yull Cho
Jun 1, 1985·Kisaengch'unghak chapchi. The Korean journal of parasitology·Chul Yong SongSang Rin Jeon
Dec 1, 1984·Kisaengch'unghak chapchi. The Korean journal of parasitology·Jong Yil ChaiSoon Hyung Lee
Jun 1, 1983·Kisaengch'unghak chapchi. The Korean journal of parasitology·Shin Yong KangDu Hwan Jang
Dec 1, 1981·Kisaengch'unghak chapchi. The Korean journal of parasitology·Jung Bin LeeSeung Yull Cho
Dec 1, 1969·Kisaengch'unghak chapchi. The Korean journal of parasitology·Byong Seol Seo, Nam Tae Hong
Nov 1, 1952·Proceedings of the Society for Experimental Biology and Medicine·E E FISCHELC PHOTOPOULOS
May 1, 1965·Parasitology·M A STIREWALTD R LINCICOME
Citations
Feb 8, 2013·Parasitology Research·Ming-Hsien LiHong-Kean Ooi
Jul 13, 2002·Parasitology International·Jong-Yil Chai, Soon-Hyung Lee
Nov 10, 2009·Veterinary Parasitology·Ming-Hsien LiChia-Kwung Fan
Mar 1, 2015·Parasitology International·Hudson Alves PintoAlan Lane de Melo
Nov 4, 2009·The Korean Journal of Parasitology·Jong-Yil ChaiHan-Jong Rim
Apr 17, 2001·The Korean Journal of Parasitology·J Y ChaiS H Lee
Jul 10, 2001·The Korean Journal of Parasitology·S H Lee, J Y Chai
Dec 1, 2006·Advances in Parasitology·Rafael ToledoBernard Fried
Jul 9, 2002·The Journal of Parasitology·J Y ChaiS H Lee
Jun 1, 1997·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·D W DenningR E Warren
Dec 20, 2018·International Journal of Veterinary Science and Medicine·Bannak G D SumuduniAppudurai Arulkanthan
Mar 31, 2021·The Journal of Parasitology·Daniel M FitzpatrickBrian P Butler