Invasive cancer of the vulva

Gynecologic Oncology
C Rosén, H Malmström

Abstract

This study comprised 328 patients with histologically confirmed primary invasive vulvar cancer, treated between 1948 and 1994. It retrospectively analyzes survival rates in relation to various prognostic factors. Mean and median age at diagnosis was 69 years (n = 328). The patients had experienced various symptoms on an average of 16.3 months prior to diagnosis (median, 6 months). Common presenting symptoms were pruritus, smarting pain, and vulvar tumor. Three hundred patients (91.5%) had squamous cell carcinomas and they were classified according to stage and tumor differentiation as follows: Stage I, 106 (35%); Stage II, 111 (37%); Stage III, 44 (15%); and Stage IV, 39 (13%); well differentiated, 107 (36%); moderately differentiated, 129 (43%); poorly or undifferentiated, 45 (15%); and in 19 cases (6%), tumor differentiation was not available. In 277 (92%) patients the primary treatment was surgical; 189 (63%) patients additionally received radiotherapy and 13 (4%) patients were also given chemotherapy. In 18 patients (6%), the primary treatment was radiotherapy and 5 of these also received chemotherapy. Two patients were given primary chemotherapy and three patients received no treatment. Median survival rate was not reached...Continue Reading

References

Dec 2, 1991·International Journal of Cancer. Journal International Du Cancer·K J AubornH L Bradlow
Nov 1, 1991·Genes, Chromosomes & Cancer·M J WorshamT E Carey
May 1, 1990·Obstetrics and Gynecology·L A BrintonR M Richart
Apr 15, 1985·Cancer·K MabuchiI I Kessler
Jun 1, 1980·Gynecologic Oncology·T IversenP Kolstad

❮ Previous
Next ❯

Citations

Mar 10, 2001·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·J. MenczerB. Modan
Mar 10, 2001·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·J. Menczer
Dec 7, 2007·Obstetrics and Gynecology Clinics of North America·Thinh H Duong, Lisa C Flowers
Dec 24, 2004·Surgical Oncology·A-T VlastosG Vlastos
Jul 11, 2006·Critical Reviews in Oncology/hematology·J A de Hullu, A G J van der Zee
Jan 16, 1999·Gynecologic Oncology·F QureshiS M Jacques
Feb 2, 2015·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·F HintenJ A de Hullu
Jul 25, 2000·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·C M LeysD M Mahvi
Sep 11, 2018·Oncology Letters·Jiang-Chun WuYu-Qin Zhang

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.