Invasive candidiasis in intensive care units in China: Risk factors and prognoses of Candida albicans and non-albicans Candida infections

American Journal of Infection Control
Xiaoying GongBin Zang

Abstract

To investigate the risk factors and prognoses of patients with invasive Candida albicans and non-albicans Candida (NAC) infection in intensive care units (ICUs) in China. Between November 2009 and April 2011, we performed a prospective study of critically ill patients with invasive Candida infection from 67 ICUs across China to compare the risk factors and mortality between patients with C albicans and NAC infection. There were 306 patients with proven invasive Candida; 244 cases (a total 389 Candida isolates) were sent to laboratory for strain identification (C albicans, 40.1%; NAC, 59.9%). More patients admitted for surgery or trauma had NAC infection than C albicans infection. C albicans infection was more common in patients with subclavian vein catheters or peritoneal drainage tubes. Compared with patients with C albicans infection, patients with NAC infection had longer antifungal therapy (P < .001), longer ICU (P = .004) or hospital stay (P = .002), and slightly higher mortality (38.4% vs 29.6%), but the difference was not significant (P = .17). C albicans remains the most common pathogen in candidiasis in critical care patients. However, the number of NAC infections exceeded C albicans infections. Compared with patients ...Continue Reading

References

Jan 1, 1995·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J R Wingard
Nov 25, 1998·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J R ReesA L Reingold
Aug 19, 1999·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·C ViscoliF Meunier
Nov 3, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J R PerfectUNKNOWN Mycoses Study Group
Dec 31, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Peter G PappasUNKNOWN Infectious Diseases Society of America
Feb 6, 2004·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Yun-Liang YangHsiu-Jung Lo
Feb 6, 2004·Diagnostic Microbiology and Infectious Disease·Ming-Fang ChengHsiu-Jung Lo
Jul 29, 2004·International Journal of Systematic and Evolutionary Microbiology·Hui-Zhong LuFeng-Yan Bai
Jan 18, 2005·Clinical Microbiology Reviews·Nina Singh, David L Paterson
Jan 16, 2007·Clinical Microbiology Reviews·M A Pfaller, D J Diekema
Jan 18, 2008·Critical Care : the Official Journal of the Critical Care Forum·Guo-Hao XieBao-Li Cheng
Feb 19, 2008·Critical Care : the Official Journal of the Critical Care Forum·Marie MéanThierry Calandra
Mar 18, 2008·Diagnostic Microbiology and Infectious Disease·Stijn BlotKoenraad Vandewoude
May 16, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·David L HornKaren M Webster
Jul 23, 2009·The Journal of Antimicrobial Chemotherapy·Matteo BassettiClaudio Viscoli
Oct 31, 2009·American Journal of Infection Control·Anucha ApisarnthanarakLinda M Mundy
Dec 3, 2009·JAMA : the Journal of the American Medical Association·Jean-Louis VincentUNKNOWN EPIC II Group of Investigators
Jan 27, 2010·Seminars in Respiratory and Critical Care Medicine·Jose A Vazquez
Apr 17, 2010·Burns : Journal of the International Society for Burn Injuries·Jennifer F HaFiona M Wood
Apr 30, 2010·Drugs·E Geoffrey PlayfordTania C Sorrell
Dec 21, 2010·Critical Care Medicine·Daniel H KettUNKNOWN Extended Prevalence of Infection in ICU Study (EPIC II) Group of Investigators
Dec 24, 2010·Virulence·Themistoklis KourkoumpetisEleftherios Mylonakis
Apr 29, 2011·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Hung-Wei ChiJung-Chung Lin
Jul 4, 2012·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Kivanc SerefhanogluF Nurhan Ozdemir
Apr 2, 2013·The Journal of Antimicrobial Chemotherapy·Fengmei GuoUNKNOWN China-SCAN Team

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Citations

Jan 31, 2018·Frontiers of Medicine·Min ChenWanqing Liao
Jan 28, 2017·Frontiers in Microbiology·Sarah G WhaleyP David Rogers
Aug 21, 2020·Emerging Infectious Diseases·Ling-Hong ZhouLi-Ping Zhu
Feb 22, 2021·Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]·Heliara Maria Spina CanelaMárcia Eliana da Silva Ferreira
May 11, 2021·Mycoses·Marly Alejandra Gavilanes-MartínezAna María García

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