Invasive candidiasis in the ICU: evidence based and on the edge of evidence

Mycoses
Eike Hollenbach

Abstract

Invasive candidiasis is a common nosocomial infection among critically ill patients, constitutes an important cause of sepsis, and is associated with significant morbidity and mortality. The Infectious Diseases Society of America (IDSA) has created evidence-based guidelines for the management of invasive candidiasis. However, several new antifungal agents with excellent activity against Candida spp. and favourable safety profiles have been introduced successfully in the clinical setting since the IDSA guidelines were published in late 2003. Further, the role of antifungals is not entirely clear in the intensive care unit (ICU) setting. Therefore, this article discusses daily problems in the prophylaxis and treatment of invasive candidasis in interdisciplinary ICUs.

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Citations

May 26, 2009·Revista iberoamericana de micología·Juan Carlos Pozo-Laderas
Apr 28, 2010·Journal of Clinical Microbiology·Tomotaka SatoNobuyoshi Shimizu
Aug 5, 2010·Critical Care Medicine·Jeannina A Smith, Carol A Kauffman
Oct 16, 2014·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Chih-Chen LinWei-Sheng Wang
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May 18, 2010·Hospital Practice·Sujatha Krishnan, Luis Ostrosky-Zeichner
Sep 25, 2012·Journal of Medical Microbiology·Y H SamaranayakeL P Samaranayake

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