Invasive carcinoma originating in an intraductal papillary mucinous neoplasm of the pancreas: a clinicopathologic comparison with a common type of invasive ductal carcinoma

Pancreas
Kazuaki ShimadaNobuyoshi Hiraoka

Abstract

Intraductal papillary mucinous neoplasm (IPMN) of the pancreas is an indolent neoplasm by nature; however, it sometimes acquires invasive potential and has been classified as invasive IPMN. The aim of the present study was to investigate the clinicopathologic difference between invasive IPMN and a common type of invasive ductal carcinoma of the pancreas. Eighteen patients with invasive IPMN underwent pancreatectomy between 1992 and 2004. Clinical, biochemical, and histopathologic factors were retrospectively analyzed. The resulting data were compared with those of 274 patients with a common type of pancreatic ductal carcinoma who underwent surgery during the same period. The total size of tumor of invasive IPMN, including cystic and invasive components, was statistically larger than that of a common type of invasive ductal carcinoma (62 vs 40 mm, P < 0.001), but the size of invasive component of invasive IPMN was smaller than that of a common type of invasive ductal carcinoma (21 vs 40 mm, P < 0.001). Negative lymph node metastases and relatively limited local tumor spreading were frequently observed in patients with invasive IPMN. On microscopic examination, the tumors infiltrating the surrounding tissue had a less invasive gr...Continue Reading

References

Oct 16, 2002·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Koji YamaguchiMasao Tanaka
Oct 19, 2002·The American Journal of Gastroenterology·Massimo RaimondoEugene P DiMagno
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Apr 16, 2004·Pancreas·Yutaka SuzukiUNKNOWN Japanese multiinstitutional study of intraductal papillary mucinous tumor and mucinous cystic tumor
May 29, 2004·Annals of Surgery·Taylor A SohnKeith D Lillemoe

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Citations

Aug 27, 2010·Surgery Today·Yoshiyuki NakajimaMasayuki Sho
Aug 19, 2007·Annals of Surgical Oncology·Toshio NakagohriNaoto Gotohda
Sep 3, 2010·Annals of Surgical Oncology·Hamed KargozaranSingh Gagandeep
Jan 8, 2013·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·S CaponiU Boggi
Mar 26, 2011·Pathology·Christopher J ScarlettJames Kench
Sep 4, 2009·Journal of Hepato-biliary-pancreatic Sciences·Toshio NakagohriTakehide Asano
Nov 12, 2020·Journal of Hepato-biliary-pancreatic Sciences·Xiu-Ping ZhangRong Liu
Jan 29, 2008·Journal of Clinical Gastroenterology·Orlin BelyaevWaldemar Uhl
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Feb 22, 2012·Gastroenterology Clinics of North America·Won Jae Yoon, William R Brugge
Jul 27, 2012·Gastroenterología y hepatología·Salvador Navarro Colás, Eva C Vaquero Raya

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