Invasive cardiopulmonary exercise testing in the evaluation of unexplained dyspnea: Insights from a multidisciplinary dyspnea center

European Journal of Preventive Cardiology
Wei HuangAaron B Waxman

Abstract

Background Unexplained dyspnea is a common diagnosis that often results in repeated diagnostic testing and even delayed treatments while a determination of the cause is being investigated. Through a retrospective study, we evaluated the diagnostic efficacy of a multidisciplinary dyspnea evaluation center (MDEC) using invasive cardiopulmonary exercise test to diagnose potential causes of unexplained dyspnea. Methods We reviewed the medical records of all patients referred with unexplained dyspnea to the MDEC between March 2011 and October 2014. We assessed the diagnostic efficacy before and after presentation to the MDEC. Results During the study period a total of 864 patients were referred to the MDEC and, of those, 530 patients underwent further investigation with invasive cardiopulmonary exercise test and constituted the study sample. The median age was 57 (44-68) years, 67.2% were women, and median body mass index was 26.22 (22.78-31.01). A diagnosis was made in 530 patients including: exercise pulmonary arterial hypertension of 88 (16.6%), heart failure with preserved ejection fraction of 94 (17.7%), dysautonomia 112 (21.1%), oxidative myopathy of 130 (24.5%), primary hyperventilation of 43 (8.1%), and other 58 (10.9%). The...Continue Reading

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Citations

Jul 1, 2017·European Journal of Preventive Cardiology·Massimo F Piepoli
May 8, 2018·Circulation·John J Ryan, Aaron B Waxman
Oct 26, 2018·European Journal of Preventive Cardiology·Francesca M RighiniPiergiuseppe Agostoni
Nov 1, 2018·European Journal of Preventive Cardiology·Carl J LavieRoss Arena
Feb 14, 2019·European Journal of Preventive Cardiology·Cosimo CarrierePiergiuseppe Agostoni
Jun 13, 2019·European Journal of Preventive Cardiology·Massimo F Piepoli
Dec 29, 2019·European Journal of Heart Failure·Markus S AnkerStefan D Anker
Oct 24, 2018·European Journal of Preventive Cardiology·Damiano Magrì
Jan 8, 2020·European Heart Journal Supplements : Journal of the European Society of Cardiology·Massimo F PiepoliGiuseppe Rosano
Feb 23, 2019·European Journal of Preventive Cardiology·Massimo F Piepoli
Dec 2, 2020·Annals of the American Thoracic Society·J Alberto Neder
Nov 20, 2020·International Journal of Cardiology·Fernando Luís ScolariAndreia Biolo
Jun 1, 2020·Chest·C Charles Jain, Barry A Borlaug
Sep 6, 2020·Heart Failure Clinics·Peter WohlfahrtJohn J Ryan
Apr 2, 2021·Annals of the American Thoracic Society·Rubabin ToobaAdriano R Tonelli
Jun 11, 2021·Journal of Cardiovascular Translational Research·Pieter MartensJan Verwerft
Feb 11, 2021·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Danilo Cortozi BertonMarcelo Basso Gazzana
Sep 22, 2019·Respiratory Medicine·J Alberto NederUNKNOWN Canadian Respiratory Research Network
Nov 30, 2021·Pneumologie·Ralf EwertChristian F Opitz

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Software Mentioned

iCPET
MDEC
niCPET
SPSS

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