Invasive Haemophilus influenzae Disease in Adults ≥65 Years, United States, 2011

Open Forum Infectious Diseases
Amy BlainElizabeth Briere

Abstract

Since the introduction of the Haemophilus influenzae serotype b vaccine, H influenzae epidemiology has shifted. In the United States, the largest burden of disease is now in adults aged ≥65 years. However, few data exist on risk factors for disease severity and outcome in this age group. A retrospective case-series review of invasive H influenzae infections in patients aged ≥65 years was conducted for hospitalized cases reported to Active Bacterial Core surveillance in 2011. There were 299 hospitalized cases included in the analysis. The majority of cases were caused by nontypeable H influenzae, and the overall case fatality ratio (CFR) was 19.5%. Three or more underlying conditions were present in 63% of cases; 94% of cases had at least 1. Patients with chronic heart conditions (congestive heart failure, coronary artery disease, and/or atrial fibrillation) (odds ratio [OR], 3.27; 95% confidence interval [CI], 1.65-6.46), patients from private residences (OR, 8.75; 95% CI, 2.13-35.95), and patients who were not resuscitate status (OR, 2.72; 95% CI, 1.31-5.66) were more likely to be admitted to the intensive care unit (ICU). Intensive care unit admission (OR, 3.75; 95% CI, 1.71-8.22) and do not resuscitate status (OR, 12.94; 95%...Continue Reading

References

Feb 1, 1987·Archives of Internal Medicine·H M Crowe, R E Levitz
Jul 1, 1995·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·W I NajmL Spurgeon
Jun 1, 1996·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·G UrwinM M Farley
Mar 27, 2001·Emerging Infectious Diseases·A SchuchatUNKNOWN Active Bacterial Core Surveillance Team of the Emerging Infections Program Network
May 3, 2003·Computer Methods and Programs in Biomedicine·Catherine Delvenne, Françoise Pasleau
Jul 5, 2003·Journal of Clinical Microbiology·Joshua M O'NeillGordon E Schutze
Feb 14, 2006·Lancet·Bruce G Link, Jo C Phelan
Mar 3, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·David GreenbergRon Dagan
Feb 17, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Mark S DworkinStephanie M Borchardt
Dec 6, 2008·The Pediatric Infectious Disease Journal·Timothy F MurphyStephen I Pelton
Mar 31, 1931·The Journal of Experimental Medicine·M Pittman
Dec 8, 2010·Journal of Pain & Palliative Care Pharmacotherapy·UNKNOWN Centers for Disease Control and Prevention Public Health Service U. S. Department of Health and Human Services
Feb 1, 2011·International Journal of Medical Microbiology : IJMM·Xin WangLeonard W Mayer
Sep 6, 2011·Emerging Infectious Diseases·Matthew P RubachAndrew T Pavia
Nov 15, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jessica R MacNeilNancy E Messonnier
Aug 21, 2012·The Journal of Infection·Daniel J LivorsiMonica M Farley

❮ Previous
Next ❯

Citations

Aug 21, 2015·Emerging Infectious Diseases·Gayle LangleyChris Van Beneden
Oct 8, 2016·Enfermedades infecciosas y microbiología clínica·Sara Fuente CosíoPedro Llinares Mondejar
Mar 18, 2017·Infectious Diseases·Lene Fogt Lundbo, Thomas Benfield
Mar 7, 2018·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Heidi M SoetersElizabeth C Briere
Jun 27, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Heidi M SoetersMichael G Bruce
Feb 9, 2017·Cancer Control : Journal of the Moffitt Cancer Center·Vivek SinghJohn N Greene
Mar 29, 2021·The Journal of Infection·Nora ChekrouniDiederik van de Beek

❮ Previous
Next ❯

Methods Mentioned

BETA
PCR

Software Mentioned

SAS

Related Concepts

Related Feeds

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Related Papers

Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)
B Fernández RodríguezS Negreira Cepeda
© 2022 Meta ULC. All rights reserved