Invasive lobular carcinoma of the breast: MRI pathological correlation following bilateral total mastectomy

Acta Radiologica
Aude StivaletAlain Rahmouni

Abstract

Invasive lobular carcinoma (ILC) is more often multifocal and bilateral than invasive ductal carcinoma. MRI is usually recommended for detection of all ILC sites. The performance of known diagnostic breast MRI criteria for ILC characterization has not been evaluated to date using bilateral mastectomy specimens as gold standard. To determine the value of BI-RADS 2006 MRI criteria for ILC detection and characterization, using pathological examination of bilateral mastectomy specimens as the reference standard. Between 2004 and 2007, we retrospectively included all patients with pathologically documented ILC referred to our institution for bilateral mastectomy and preoperative bilateral breast MRI. The location, diameter, and characteristics (BI-RADS) of all lesions were compared with pathological findings. The sensitivity and positive predictive value of bilateral breast MRI for the diagnosis of ILC were calculated. Association of MRI BI-RADS categorical variables and characterization of ILC were assessed (Fisher exact test). Among 360 patients treated for ILC in 2004-2007, 15 patients qualified for this study. Thirty-one ILC foci were found on pathological examination (30 ipsilateral and 1 contralateral tumor; mean diameter 23 m...Continue Reading

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Citations

Jan 19, 2013·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Délio Marques CondeElbio Cândido de Paula
Jan 13, 2006·Gynécologie, obstétrique & fertilité·M EspiéA de Roquancourt
May 11, 2013·World Journal of Surgery·Armen ParsyanSarkis Meterissian

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biopsies
biopsy

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