Invasive pulmonary aspergillosis with spontaneous resolution and the diagnostic utility of PCR from tissue specimens

The Journal of Infection
William W HopeDavid W Denning

Abstract

This case describes a 61-year-old apparently immunocompetent female with invasive pulmonary aspergillosis (IPA) and eosinophilia who demonstrated spontaneous clinical and radiological recovery. The patient had a history of asthma and had been corticosteroid dependent until 2 months prior to her presentation. This report explores the role of PCR in confirming the diagnosis of invasive aspergillosis in circumstances where only histological data are available and highlights the fact that invasive infections with Aspergillus spp. can occur without profound immunological deficiency. The case also documents the resolution of IPA without specific therapy.

Citations

Nov 18, 2005·The Journal of Infection·S C C RibeiroT Y Takagaki
Aug 23, 2005·Medical Mycology·D Buchheidt, M Hummel
Sep 1, 2006·Medical Mycology·P Lewis White, Rosemary A Barnes

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