Inverse cutting of posterior lamellar corneal grafts by a femtosecond laser.

The Open Ophthalmology Journal
Jesper HjortdalAnders Søndergaard

Abstract

Posterior lamellar grafting of the cornea has become the preferred technique for treatment of corneal endothelial dysfunction. Posterior lamellar grafts are usually cut by a micro-keratome or a femto-second laser after the epithelial side of the donor cornea has been applanated. This approach often results in variable central graft thickness in different grafts and an increase in graft thickness towards the periphery in every graft. The purpose of this study was to evaluate if posterior lamellar grafts can be prepared from the endothelial side by a femto-second laser, resulting in reproducible, thin grafts of even thickness. A CZM 500 kHz Visumax femto-second laser was used. Organ cultured donor grafts were mounted in an artifical anterior chamber with the endothelial side up and out. Posterior grafts of 7.8 mm diameter and 130 micron thickness were prepared by femto-second laser cutting. A standard DSAEK procedure was performed in 10 patients with Fuchs endothelial dystrophy. Patients were followed-up regularly and evaluated by measurement of complications, visual acuity, corneal thickness (Pentacam HR), and endothelial cell density. Femto-laser cutting of grafts and surgery was uncomplicated. Rebubbling was necessary in 5 of ...Continue Reading

Citations

May 11, 2013·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·S HeinzelmannT Reinhard
Mar 28, 2013·The British Journal of Ophthalmology·Andreia Martins RosaJoaquim Neto Murta
Dec 13, 2012·Journal of Refractive Surgery·George D KymionisDan Z Reinstein
Jul 12, 2017·Journal of Ophthalmology·Mohamed H HosnyMohsen Salem
Oct 16, 2020·Vestnik oftalmologii·N F ShilovaB E Malyugin
Feb 2, 2021·Survey of Ophthalmology·Rashmi DeshmukhRasik B Vajpayee

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