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Inverse Medea as a novel gene drive system for local population replacement: a theoretical analysis

The Journal of Heredity

Jan 1, 2011

John M. Marshall, Bruce A. Hay

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Abstract

One strategy to control mosquito-borne diseases, such as malaria and dengue fever, on a regional scale is to use gene drive systems to spread disease-refractory genes into wild mosquito populations. The development of a synthetic Medea element that has been shown to drive population rep...read more

Mentioned in this Paper

Genetic Analysis
Malaria Pathway
Antidote
Genetic Screening Method
Malaria Vaccines
Malaria
Sample Fixation
Antidote [EPC]
Transgenes
Insect Vectors
65
Paper Details
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    • References16
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  • Inverse Medea as a novel gene drive system for local population replacement: a theoretical analysis

    The Journal of Heredity

    Jan 1, 2011

    John M. Marshall, Bruce A. Hay

    PMID: 21493596

    DOI: 10.1093/jhered/esr019

    Abstract

    One strategy to control mosquito-borne diseases, such as malaria and dengue fever, on a regional scale is to use gene drive systems to spread disease-refractory genes into wild mosquito populations. The development of a synthetic Medea element that has been shown to drive population rep...read more

    Mentioned in this Paper

    Genetic Analysis
    Malaria Pathway
    Antidote
    Genetic Screening Method
    Malaria Vaccines
    65

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    References
    • References16
    • Citations10
    • References16
    • Citations10
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