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Inverse Medea as a novel gene drive system for local population replacement: a theoretical analysis

The Journal of Heredity

Apr 16, 2011

John M Marshall, Bruce A Hay

Abstract

One strategy to control mosquito-borne diseases, such as malaria and dengue fever, on a regional scale is to use gene drive systems to spread disease-refractory genes into wild mosquito populations. The development of a synthetic Medea element that has been shown to drive population rep...read more

Mentioned in this Paper

Dengue Fever
Toxin
Genetic Analysis
Genetic Screening Method
Sample Fixation
Drosophila
Insect Vectors
Malaria
Malaria Vaccines
Psathyrella
66
Paper Details
References
  • References16
  • Citations12
12
  • References16
  • Citations12
12

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Inverse Medea as a novel gene drive system for local population replacement: a theoretical analysis

The Journal of Heredity

Apr 16, 2011

John M Marshall, Bruce A Hay

PMID: 21493596

DOI: 10.1093/jhered/esr019

Abstract

One strategy to control mosquito-borne diseases, such as malaria and dengue fever, on a regional scale is to use gene drive systems to spread disease-refractory genes into wild mosquito populations. The development of a synthetic Medea element that has been shown to drive population rep...read more

Mentioned in this Paper

Dengue Fever
Toxin
Genetic Analysis
Genetic Screening Method
Sample Fixation
Drosophila
Insect Vectors
Malaria
Malaria Vaccines
Psathyrella
66

Similar Papers Found In These Feeds

Plasmodium Falciparum

Malaria remains a major cause of morbidity and mortality in the tropics, with the parasite Plasmodium falciparum responsible for the majority of the disease burden. Discover the latest research on Plasmodium falciparum.

Malaria Vaccines

Research for development of a malaria vaccine is currently underway to find an effective modality to control and eliminate the transmission of malaria. To date, no vaccine has been found to be efficacious in fighting against malaria. Here is the latest research on malaria vaccines.

Related Papers

Journal of Theoretical Biology

Confinement of gene drive systems to local populations: a comparative analysis

Journal of Theoretical BiologyNovember 19, 2011
John M Marshall, Bruce A Hay
Paper Details
References
  • References16
  • Citations12
12
  • References16
  • Citations12
12
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