PMID: 18400724Apr 11, 2008Paper

Inverse relation between dietary intake of naturally occurring plant sterols and serum cholesterol in northern Sweden

The American Journal of Clinical Nutrition
Sofia KlingbergAnna Winkvist

Abstract

Plant sterols are bioactive compounds, found in all vegetable foods, which inhibit cholesterol absorption. Little is known about the effect of habitual natural dietary intake of plant sterols. We investigated the relation between plant sterol density (in mg/MJ) and serum concentrations of cholesterol in men and women in northern Sweden. The analysis included 37 150 men and 40 502 women aged 29-61 y, all participants in the Västerbotten Intervention Program. Higher plant sterol density was associated with lower serum total cholesterol in both sexes and with lower LDL cholesterol in women. After adjustment for age, body mass index (in kg/m(2)), and (in women) menopausal status, men with high plant sterol density (quintile 5) had 0.15 mmol/L (2.6%) lower total serum cholesterol (P for trend = 0.001) and 0.13 mmol/L (3.1%) lower LDL cholesterol (P = 0.062) than did men with low plant sterol density (quintile 1). The corresponding figures for women were 0.20 mmol/L (3.5%) lower total serum cholesterol (P for trend < 0.001) and 0.13 mmol/L (3.2%) lower LDL cholesterol (P for trend = 0.001). The present study is the second epidemiologic study to show a significant inverse relation between naturally occurring dietary plant sterols and ...Continue Reading

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Citations

Sep 30, 2009·Journal of Lipid Research·Verónica EscurriolEmilio Ros
Apr 2, 2010·Journal of Physiology and Biochemistry·T SanclementeA L García-Otín
Jul 11, 2009·Journal of Physiology and Biochemistry·T SanclementeA L García-Otín
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May 5, 2009·European Journal of Nutrition·Verónica EscurriolEmilio Ros
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Nov 4, 2021·American Journal of Physiology. Gastrointestinal and Liver Physiology·Sik Yu So, Tor C Savidge

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