Inverse Relationship Between Physical Activity, Adiposity, and Arterial Stiffness in Healthy Middle-Aged Subjects

Journal of Physical Activity & Health
Oscar Mac AnaneyVincent Maher

Abstract

Several obesity related factors are reported to exacerbate premature arterial stiffening, including inactivity and metabolic disarray. The aim of the current study was to investigate the relationship between physical activity, arterial stiffness and adiposity using objective methods. To further explore the role of adiposity in this complex process, obesity associated anthropometric and humoral biomarkers were measured. Seventy-nine healthy, lifelong nonsmoking subjects were recruited. Habitual physical activity was measured using accelerometry. Arterial stiffness [augmentation index (AIx) and pulse wave velocity (PWV)] was measured using tonometry. Body composition was estimated using bioimpedence. Adipose associated biomarkers, leptin and adiponectin, were also measured. Sedentary time was significantly associated with AIx (r = 0.38, P < .001), PWV (r = 0.33, P < .01), body fat composition (r = 0.40, P < .001) and age (r = 0.30, P < .01). Moderate-to-vigorous physical activity (MVPA) was inversely correlated with AIx (r = -0.28, P < .05), body fat composition (r = -0.30, P < .01), postprandial insulin (r = -0.35, P < .01), and leptin/adiponectin ratio (r = -0.28, P < .05). MVPA, body fat composition, and postprandial insulin r...Continue Reading

Citations

Dec 2, 2020·Public Health Nutrition·Bruna Clemente CotaSylvia do Carmo Castro Franceschini

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