Inversion of perceived direction of motion caused by spatial undersampling in two children with periventricular leukomalacia

Journal of Cognitive Neuroscience
Maria Concetta MorroneGiovanni Cioni

Abstract

We report here two cases of two young diplegic patients with cystic periventricular leukomalacia who systematically, and with high sensitivity, perceive translational motion of a random-dot display in the opposite direction. The apparent inversion was specific for translation motion: Rotation and expansion motion were perceived correctly, with normal sensitivity. It was also specific for random-dot patterns, not occurring with gratings. For the one patient that we were able to test extensively, contrast sensitivity for static stimuli was normal, but was very low for direction discrimination at high spatial frequencies and all temporal frequencies. His optokinetic nystagmus movements were normal but he was unable to track a single translating target, indicating a perceptual origin of the tracking deficit. The severe deficit for motion perception was also evident in the seminatural situation of a driving simulation video game. The perceptual deficit for translational motion was reinforced by functional magnetic resonance imaging studies. Translational motion elicited no response in the MT complex, although it did produce a strong response in many visual areas when contrasted with blank stimuli. However, radial and rotational moti...Continue Reading

References

Feb 1, 1985·Journal of the Optical Society of America. A, Optics and Image Science·E H Adelson, J R Bergen
Feb 29, 1980·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·S Zeki
Feb 1, 1983·Perception & Psychophysics·A B Watson, D G Pelli
Aug 10, 1995·Nature·M C MorroneL M Vaina
May 1, 1994·Cerebral Cortex·T Pasternak, W H Merigan
Apr 16, 1996·Proceedings of the National Academy of Sciences of the United States of America·D PurvesT J Andrews
Dec 31, 1997·Cerebral Cortex·S Van OostendeG A Orban
Jan 22, 1998·Pediatric Neurology·G CioniJ van Hof-van Duin
May 20, 1998·Journal of Neurophysiology·L CornetteG A Orban
Nov 3, 1998·Vision Research·D C BurrL M Vaina
Dec 16, 1998·Developmental Medicine and Child Neurology·E FedrizziS Savoiardo
May 2, 2000·Vision Research·M A Georgeson, N E Scott-Samuel
Dec 2, 2000·Nature Neuroscience·M C MorroneD C Burr
Mar 22, 2001·Perception·O J BraddickR Turner
May 9, 2002·Neuroreport·Alison GunnGiovanni Cioni
Feb 13, 2004·Perception·Pooya Pakarian, Mohammad Taghi Yasamy
Jun 25, 2005·Brain : a Journal of Neurology·Lucia M VainaRon Kikinis
Nov 24, 2005·Current Biology : CB·Shinichi KoyamaTakeo Watanabe
Jan 20, 2006·The European Journal of Neuroscience·A T SmithK D Singh
Jan 2, 2007·Nature Neuroscience·Giovanni d'AvossaMaria Concetta Morrone

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Citations

Sep 30, 2015·PLoS Biology·Laura BiagiMaria Concetta Morrone
Sep 8, 2009·Neuroreport·Andrea GuzzettaGiovanni Cioni

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