Invertebrates as a source of emerging human pathogens

Nature Reviews. Microbiology
Nicholas WaterfieldR H ffrench-Constant

Abstract

Despite their importance, little is known about the origins of many emerging human pathogens. However, given the age and current predominance of invertebrates, it is likely that bacteria-invertebrate interactions are not only a present source of human pathogens but have also shaped their evolution. Pathogens of invertebrate and unicellular organisms represent an extensive reservoir of bacterial strains equipped with virulence factors that evolved to overcome the innate immune responses of their hosts. This reservoir might represent a source of new human pathogenic strains and might also foster the spread of novel virulence factors into existing human commensal or pathogenic bacteria. This article examines the available evidence for this concept by examining pairs of closely related bacteria, one of which is benign, but insect associated, and one of which is a human pathogen.

References

Nov 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·J M GonzálezB C Carlton
Jan 1, 1997·Clinical Microbiology Reviews·R D Perry, J D Fetherston
Jan 1, 1997·Annual Review of Entomology·J P GillespieT Trenczek
Jan 1, 1997·Annual Review of Microbiology·S ForstE Stackebrandt
Mar 14, 1998·Proceedings of the National Academy of Sciences of the United States of America·L MargulisS C Lo
Jun 26, 1998·Science·D BowenR H ffrench-Constant
Sep 8, 1998·Microbiology and Molecular Biology Reviews : MMBR·E SchnepfD H Dean
Sep 4, 1999·Journal of Applied Microbiology·J W Ezzell, S L Welkos
Nov 26, 1999·Proceedings of the National Academy of Sciences of the United States of America·M AchtmanE Carniel
Jun 1, 2000·Applied and Environmental Microbiology·E HelgasonA B Kolstø
Aug 5, 2000·Applied and Environmental Microbiology·R H Ffrench-ConstantF R Blattner
Aug 2, 2000·Proceedings of the National Academy of Sciences of the United States of America·G R Cornelis
Dec 9, 2000·International Journal of Medical Microbiology : IJMM·D LereclusM Gominet
Apr 5, 2001·Trends in Microbiology·N R WaterfieldR H ffrench-Constant
Mar 26, 2002·Trends in Microbiology·Stephen E GirardinDana J Philpott
Apr 16, 2002·Science·Ruslan Medzhitov, Charles A Janeway
Apr 20, 2002·Cellular and Molecular Life Sciences : CMLS·A Aronson
May 15, 2002·International Journal of Medical Microbiology : IJMM·Michelle L ZaharikB Brett Finlay
May 17, 2002·Nature·Creg DarbyStanley Falkow
Jul 24, 2002·Proceedings of the National Academy of Sciences of the United States of America·P J DabornR H Ffrench-Constant
Jul 27, 2002·Journal of Bacteriology·Wen DengRobert D Perry
Sep 13, 2002·Insect Biochemistry and Molecular Biology·M D Lavine, M R Strand
Oct 31, 2002·Molecular Microbiology·B Joseph HinnebuschElisabeth Carniel

❮ Previous
Next ❯

Citations

Jun 10, 2006·Nature Biotechnology·Richard H ffrench-Constant, Nicholas R Waterfield
Dec 24, 2009·Nature Reviews. Immunology·Javier E IrazoquiFrederick M Ausubel
Oct 8, 2008·Proceedings of the National Academy of Sciences of the United States of America·Nicholas R WaterfieldRichard H Ffrench-Constant
Apr 30, 2011·The Journal of Biological Chemistry·Joel J SheetsKlaus Aktories
Jul 20, 2010·Applied and Environmental Microbiology·Britta SpanierThilo M Fuchs
Jul 10, 2013·Applied and Environmental Microbiology·Ditte A SøborgNiels Kroer
Oct 7, 2008·Journal of Bacteriology·Larry A GallagherColin Manoil
Jul 7, 2009·Annual Review of Microbiology·Nick R WaterfieldDavid Clarke
Feb 5, 2010·Environmental Health : a Global Access Science Source·Lizeth Lacharme-LoraSarah E Perkins
Mar 8, 2007·PloS One·Joseph J GillespieAbdu F Azad
Dec 21, 2006·Emerging Infectious Diseases·John G GerrardNick R Waterfield
Mar 4, 2014·The Journal of Microbiology·Grace J Yuen, Frederick M Ausubel
Mar 20, 2014·BMC Microbiology·Julie AllombertLaurent Hébert
Oct 16, 2013·Journal of Industrial Microbiology & Biotechnology·Maria I VizcainoJason M Crawford
Aug 3, 2005·Proceedings of the National Academy of Sciences of the United States of America·Nicolas VodovarBruno Lemaitre
Dec 8, 2009·Journal of Medical Entomology·David L EricksonAndrea Jolley
Nov 3, 2010·Trends in Microbiology·Ioannis EleftherianosStuart E Reynolds
Aug 2, 2008·Microbes and Infection·Heike Feldhaar, Roy Gross
Jan 5, 2006·Molecular Microbiology·Geraldine BresolinThilo M Fuchs
May 12, 2007·Molecular Microbiology·Heidi Goodrich-Blair, David J Clarke
Aug 4, 2012·Environmental Microbiology·José L Martínez
Jul 6, 2010·Cellular Microbiology·Isabelle Vallet-GelyBruno Lemaitre
Dec 23, 2009·Letters in Applied Microbiology·A PapagiannoulisD Mossialos
Mar 21, 2006·Trends in Parasitology·Ana Rivero
Apr 14, 2005·Journal of Biochemistry and Molecular Biology·Sadaaki Iwanaga, Bok Luel Lee
Jul 8, 2015·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Jakub KreisingerSarah E Perkins
Jun 1, 2015·Toxicon : Official Journal of the International Society on Toxinology·Thomas JankKlaus Aktories
Dec 26, 2009·Microbes and Infection·Sónia C P CostaRobert Zumbihl
Feb 16, 2010·Current Biology : CB·Nick Waterfield

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.