Inverted Internal Limiting Membrane Flap Technique for Repair of Large Macular Holes: A Short-term Follow-up of Anatomical and Functional Outcomes

Chinese Medical Journal
Zhe ChenRui-Fang Sui

Abstract

Inverted internal limiting membrane (ILM) flap technique has recently been reported in a limited number of studies as an effective surgical technique for the management of large macular holes (MHs) with fair MH closure rates as well as gains in visual acuity. In the current study, longitudinal changes in multi-focal electroretinogram (mfERG) responses, best-corrected visual acuity (BCVA) and spectral-domain optical coherence tomography (SD-OCT) were evaluated in eyes with large MHs managed by this technique. A prospective noncontrolled interventional study of eight patients (eight eyes) with large MHs (minimum diameter >400 μm) was conducted. All MHs were treated with pars plana vitrectomy and indocyanine green-assisted inverted ILM flap technique. SD-OCT images were used to assess the anatomical outcomes of surgery while BCVA and mfERG were used to evaluate the functional outcomes during a 3-month follow-up. All patients underwent successful intended manipulation and translocation of the ILM flap without flap dislocation and achieved complete anatomical closure. Partial microstructural reconstruction, demonstrated on SD-OCT as restoration of the external limiting membrane and the ellipsoid zone, was observed in all cases as ea...Continue Reading

References

May 1, 1991·Archives of Ophthalmology·N E Kelly, R T Wendel
Nov 30, 1999·American Journal of Ophthalmology·M ImaiS Tsukahara
Aug 2, 2000·Archives of Ophthalmology·K KadonosonoS Ohno
Jul 28, 2001·Documenta Ophthalmologica. Advances in Ophthalmology·M MoschosG Theodossiadis
Nov 14, 2002·American Journal of Ophthalmology·Michael N ApostolopoulosGeorge P Theodossiadis
Jul 26, 2003·The British Journal of Ophthalmology·S W KangD-I Ham
Apr 4, 2008·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Zofia MichalewskaJerzy Nawrocki
May 13, 2009·Acta Ophthalmologica·Paul B HenrichSiegfried Priglinger
Jun 15, 2010·Ophthalmology·Zofia MichalewskaJerzy Nawrocki
Nov 1, 2011·Documenta Ophthalmologica. Advances in Ophthalmology·Donald C HoodUNKNOWN International Society For Clinical Electrophysiology of Vision
Apr 30, 2013·American Journal of Ophthalmology·Shoji KuriyamaMiho Matsumoto
Nov 12, 2013·Indian Journal of Ophthalmology·Prabhushanker Mahalingam, Kumar Sambhav

❮ Previous
Next ❯

Citations

Feb 27, 2018·International Journal of Retina and Vitreous·Raul Velez-MontoyaSergio E Hernandez-Da Mota
Feb 12, 2020·European Journal of Ophthalmology·Tommaso RossiGuido Ripandelli
Feb 6, 2017·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Tommaso RossiGuido Ripandelli
Jun 1, 2018·Journal of Ophthalmology·Peng-Peng ZhaoJin-Song Zhao

❮ Previous
Next ❯

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.