PMID: 22338220Feb 18, 2012Paper

Investigate the impact of hepatitis B virus infection on sperm DNA integrity

Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology
Jian-Wei ChenXiao-Xia Zhang

Abstract

Investigated the impact of HBV infection on sperm DNA integrity and its applied significance. 12 cases infertility male with HBV infection in patient group and 11 cases of normal male without HBV infection in the control group were by SCD and CASA. The DFI in the patient group was (23.4 +/- 10.2)%, while it was in the control group was (11.6 +/- 5.9)%. The difference of the DFI in these two groups was significantly, P < 0.01. The sperm concentration and forward motility (a + b) in the patient group were lower than that in the control group, P < 0.01. There were also significantly of the normal sperm and sperm activity between the two groups. HBV infection not only affected the conventional semen parameters, but also caused serious damage on sperm DNA.

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