journal cover

Investigating conservation of the albaflavenone biosynthetic pathway and CYP170 bifunctionality in streptomycetes

The FEBS Journal

Dec 14, 2011

Suzy C MoodyDavid C Lamb

Download from

Publisher
PubMed

Abstract

Albaflavenone, a tricyclic sesquiterpene antibiotic, is biosynthesized in Streptomyces coelicolor A3(2) by enzymes encoded in a two-gene operon. Initially, sesquiterpene cyclase catalyzes the cyclization of farnesyl diphosphate to the terpenoid epi-isozizaene, which is oxidized to the f...read more

Mentioned in this Paper

farnesyl pyrophosphate, (Z,Z)-isomer
ATTS1 protein, Arabidopsis
epi-isozizaene
Streptomyces albus
Streptomyces coelicolor
Terpene Phosphates
Amino Acids, I.V. solution additive
Streptomyces coelicolor A3(2)
Sesquiterpenes
Cytochrome P-450 Oxygenase
1
37
1
Paper Details
References
  • References21
  • Citations11
123
  • References21
  • Citations11
12

Feeds With Similar Papers

Mechanisms of CYP450

Cytochrome P450 (CYP450) are a family of enzymes involved in two major processes, such as the synthesis of fatty acids, steroids, and biles acids, and the metabolism of toxins and drugs. Discover the latest research on the Mechanisms of CYP450 enzymes here.

© 2020 Meta ULC. All rights reserved

Investigating conservation of the albaflavenone biosynthetic pathway and CYP170 bifunctionality in streptomycetes

The FEBS Journal

Dec 14, 2011

Suzy C MoodyDavid C Lamb

PMID: 22151149

DOI: 10.1111/j.1742-4658.2011.08447.x

Abstract

Albaflavenone, a tricyclic sesquiterpene antibiotic, is biosynthesized in Streptomyces coelicolor A3(2) by enzymes encoded in a two-gene operon. Initially, sesquiterpene cyclase catalyzes the cyclization of farnesyl diphosphate to the terpenoid epi-isozizaene, which is oxidized to the f...read more

Mentioned in this Paper

farnesyl pyrophosphate, (Z,Z)-isomer
ATTS1 protein, Arabidopsis
epi-isozizaene
Streptomyces albus
Streptomyces coelicolor
Terpene Phosphates
Amino Acids, I.V. solution additive
Streptomyces coelicolor A3(2)
Sesquiterpenes
Cytochrome P-450 Oxygenase
1
37
1

Feeds With Similar Papers

Mechanisms of CYP450

Cytochrome P450 (CYP450) are a family of enzymes involved in two major processes, such as the synthesis of fatty acids, steroids, and biles acids, and the metabolism of toxins and drugs. Discover the latest research on the Mechanisms of CYP450 enzymes here.

Related Papers

Paper Details
References
  • References21
  • Citations11
123
  • References21
  • Citations11
12

Download from

Publisher
PubMed
/papers/investigating-conservation-of-the-albaflavenone/22151149