Investigating the effect of intra-articular PRP injection on pain and function improvement in patients with distal radius fracture

Orthopaedics & Traumatology, Surgery & Research : OTSR
H Namazi, A Mehbudi

Abstract

Distal radius fractures are common injuries that cause pain and disability. There is a clear need for biomedical engineering research to develop novel strategies to improve functional results following intra-articular distal radius fractures. However, no pharmacotherapeutic agent has been investigated to resolve this problem. The aim of this study was to evaluate whether the platelet-rich plasma (PRP) can be considered a novel additional therapy to improve the outcomes of this injury. Pain reduction and functional improvement can be noticed after PRP use in distal radius fracture. A randomized trial study was designed with 30 patients who had intra-articular distal radius fractures (Frykman type 3, 4, 7, 8). Closed reduction and percutaneous pinning under guide of fluoroscopy were done for them. Fifteen cases received intra-articular autologus PRP. Patients were followed for 3 and 6 months and "patient-rated wrist evaluation" (PRWE) questionnaire was completed and range of motion of the wrist was measured. The mean of pain score and the score of specific and usual activities at 3 months follow-up in the case group and in the control group were (8.33 versus 19.67), (10.66 versus 26.8), and (6.2 versus 13.4), respectively. The me...Continue Reading

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Citations

Sep 28, 2017·JBJS Reviews·Dean Wang, Scott A Rodeo
Nov 26, 2019·The American Journal of Sports Medicine·Hongyao XuHe Huang
Nov 15, 2017·Future Science OA·Seyed Ahmad RaeissadatHossein Fouladi Vanda
Mar 1, 2019·Therapeutic Advances in Chronic Disease·Lucía Gato-CalvoElena F Burguera
Jan 13, 2021·Injury·Esther M M Van Lieshout, Dennis Den Hartog
May 8, 2021·The Journal of Hand Surgery·Kristin E KarimMichael S Murphy

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