Investigating the etiologic agents of aseptic meningitis outbreak in Iranian children

Journal of Family Medicine and Primary Care
Abdolkarim Ghadimi MoghadamMarzieh Jamalidoust

Abstract

This study aimed to determine the viral agent (s) and their genome burden associated with an aseptic meningitis outbreak that occurred in Yasuj, Iran. During April to August 2015, 104 CSF samples from 104 patients under 14 years old admitted to the hospital of Yasuj, Iran, with aseptic meningitis associated clinical signs were collected. 200 μl CSF specimens was prepared for DNA and RNA viral genome extraction each and then subjected to diagnostic Taq-man real time PCR assays for the present of Enteroviruses, HSV, VZV, mumps, measles and rubella in the samples. The majority of them had experienced clinical meningitis sign. Primary laboratory differentiated tests were in favor of viral meningitis. Among a total of 104 patients diagnosed with clinically aseptic meningitis, enterovirus as the most significant viral agent was detected in 53 subjects. However, mumps, HSV and VZV, as the endemic causes of viral meningitis, were detected in 6, 6 and 2 of the affected patients. It was revealed that two HSV and one VZV affected patients were co-infected with enteroviruses. All affected children with relatively variable viral load recovered without any sequels. The present study revealed enterovirus as the main predominant cause of pedia...Continue Reading

References

Jan 10, 2002·Journal of Medical Virology·Mamdoh M MeqdamAbdullah Al-Shurman
May 2, 2007·Current Opinion in Infectious Diseases·Bonita E Lee, H Dele Davies
Jun 19, 2007·Vaccine·Terhi TapiainenUNKNOWN Brighton Collaboration Aseptic Meningitis Working Group
Jul 5, 2007·Archives of Virology·G-W ChenS-C Chang
Mar 25, 2008·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Delphine BrunelLaurent Andréoletti
Apr 30, 2010·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·Vitor Laerte Pinto JuniorMárcio Neves Bóia
Mar 18, 2011·Journal of Medical Virology·Ali HosseininasabMohamad Rahim Kadivar
Feb 18, 2012·Virology Journal·Hye-Jin KimDoo-Sung Cheon
Dec 30, 2014·Virus Genes·Zaharoula KyriakopoulouPanayotis Markoulatos
Feb 11, 2016·The Pediatric Infectious Disease Journal·Henriette RudolphTobias Tenenbaum
Jan 14, 2017·Hospital Pediatrics·Sowdhamini S WallaceA Chantal Caviness
Jan 25, 2017·Current Opinion in Infectious Diseases·Fiona McGillTom Solomon
Aug 15, 2017·JAMA Pediatrics·Kristine MacartneyUNKNOWN Paediatric Active Enhanced Disease Surveillance Network
Aug 15, 2017·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Bhavarth ShuklaRodrigo Hasbun
Jun 7, 2016·Polish Journal of Microbiology·Magdalena WieczorekArleta Krzysztoszek
Nov 6, 2018·The Lancet Infectious Diseases·Jérémy LafolieUNKNOWN Blood Enterovirus Diagnosis Infection (BLEDI) in paediatric population study team
May 3, 2019·BMC Infectious Diseases·Lea Necitas ApostolHitoshi Oshitani
Jul 19, 2019·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Duah AlkamSe-Ran Jun

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Methods Mentioned

BETA
PCR
ESR

Software Mentioned

SPSS

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