Investigating the mechanism underlying urinary continence recovery after radical prostatectomy: effectiveness of a longer urethral stump to prevent urinary incontinence

BJU International
Yoshifumi KadonoAtsushi Mizokami

Abstract

To assess the chronological changes in urinary incontinence and urethral function before and after radical prostatectomy (RP), and to compare the findings of pelvic magnetic resonance imaging (MRI) before and after RP to evaluate the anatomical changes. In total, 185 patients were evaluated with regard to the position of the distal end of the membranous urethra (DMU) on a mid-sagittal MRI slice and urethral sphincter function using the urethral pressure profilometry. The patients also underwent an abdominal leak point pressure test before RP and at 10 days and 12 months after RP. The results were then compared with the chronological changes in urinary incontinence. The MRI results showed that the DMU shifted proximally to an average distance of 4 mm at 10 days after RP and returned to the preoperative position at 12 months after RP. Urethral sphincter function also worsened 10 days after RP, with recovery after 12 months. The residual length of the urethral stump and urinary incontinence were significantly associated with the migration length of the DMU at 10 days after RP. The residual length of the urethral stump was a significant predictor of urinary incontinence after RP. This is the first study to elucidate that the slight...Continue Reading

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Citations

Apr 9, 2019·Minerva urologica e nefrologica = The Italian journal of urology and nephrology·Fabio ZattoniFabrizio Dal Moro
Aug 31, 2020·Stem Cells Translational Medicine·Mariano Garcia-ArranzDamian Garcia-Olmo
Jan 24, 2019·Therapeutic Advances in Urology·Carlos ArroyoAshutosh K Tewari
Nov 6, 2020·The World Journal of Men's Health·Nicolò SchifanoAndrea Salonia

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