Investigating the phenomenon of "cognitive-motor interference" in multiple sclerosis by means of dual-task posturography

Gait & Posture
Luca ProsperiniCarlo Pozzilli

Abstract

Two simultaneously performed tasks may compete for common brain network resources in patients with multiple sclerosis (MS), suggesting the occurrence of a cognitive-motor interference. While this phenomenon has been well described for walking and gait, data on static balance are scarce. In this cross-sectional study, 92 patients and 46 sex/age-matched healthy controls (HCs) were tested by means of static posturography under eyes opened (single-task condition) and while performing the Stroop word-colour task (dual-task condition), to estimate the dual-task cost (DTC) of standing balance. The patient group also underwent the Expanded Disability Status Scale, 25-foot walking test, 12-item MS walking scale, Modified Fatigue Impact Scale, and Symbol Digit Modalities Test. Patients had larger postural sway under both single-task and dual-task conditions (p<0.001), as well as greater DTC of standing balance (p=0.021) than HCs. Although secondary progressive (SP) patients had larger sway in both conditions than relapsing-remitting (RR) patients (p<0.05), these latter ones exhibited a greater DTC of postural balance (p=0.045). Deficits in sustained attention and information processing speed, as assessed by the SDMT, were also independen...Continue Reading

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Citations

Jan 6, 2016·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Letizia CastelliLuca Prosperini
May 14, 2016·International Journal of Rehabilitation Research. Internationale Zeitschrift Für Rehabilitationsforschung. Revue Internationale De Recherches De Réadaptation·Alon Kalron
Aug 21, 2016·Archives of Physical Medicine and Rehabilitation·Yvonne C LearmonthRobert W Motl
Nov 13, 2018·Multiple Sclerosis : Clinical and Laboratory Research·Joke RaatsPeter Feys
Sep 25, 2017·Journal of the International Neuropsychological Society : JINS·Emma Butchard-MacDonaldJonathan J Evans
Oct 3, 2018·Frontiers in Behavioral Neuroscience·Anna M BarbaruloGiovannina Conchiglia
Sep 12, 2019·Frontiers in Neurology·Ludivine Chamard WitkowskiGrant Handrigan
Mar 25, 2017·Multiple Sclerosis : Clinical and Laboratory Research·Serena RuggieriLuca Prosperini
Aug 24, 2017·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Vincenzo DattolaMargherita Russo
Feb 3, 2021·The International Journal of Neuroscience·Triantafyllos DoskasΚonstantinos Vadikolias
Feb 11, 2021·Motor Control·Nathan MorelliMatthew C Hoch
Feb 5, 2021·Multiple Sclerosis and Related Disorders·Nathan Morelli, Haley Morelli
Mar 23, 2021·Journal of Vestibular Research : Equilibrium & Orientation·Anat V LubetzkyTal Krasovsky

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