Investigating the psychosocial determinants of child health in Africa: The Drakenstein Child Health Study

Journal of Neuroscience Methods
Dan J SteinH J Zar

Abstract

Early life psychobiological and psychosocial factors play a key role in influencing child health outcomes. Longitudinal studies may help elucidate the relevant risk and resilience profiles, and the underlying mechanisms that impact on child health, but there is a paucity of birth cohort data from low and middle-income countries (LMIC). We describe the rationale for and present baseline findings from the psychosocial component of the Drakenstein Child Health Study (DCHS). We review the psychosocial measures used in the DCHS, a multidisciplinary birth cohort study in a peri-urban area in South Africa, and provide initial data on psychological distress, depression, substance use, and exposure to traumatic stressors and intimate partner violence (IPV). These and other measures will be assessed longitudinally in mothers in order to investigate associations with child neurodevelopmental and health outcomes. Baseline psychosocial data is presented for mothers (n=634) and fathers (n=75) who have completed antenatal assessments to date. The sample of pregnant mothers is characterized by multiple psychosocial risk factors, including a high prevalence of psychological distress and depression, high levels of substance use, and high exposur...Continue Reading

References

Sep 1, 1991·British Journal of Addiction·T F HeathertonK O Fagerström
Jun 1, 1987·The British Journal of Psychiatry : the Journal of Mental Science·J L CoxR Sagovsky
Jan 1, 1995·Journal of Traumatic Stress·D D BlakeT M Keane
Aug 1, 1994·The American Journal of Psychiatry·D P BernsteinJ Ruggiero
Jun 5, 2001·Depression and Anxiety·F W WeathersJ R Davidson
Sep 5, 2001·The American Journal of Psychiatry·A BrunetC R Marmar
Apr 30, 2002·Lancet·Rachel Jewkes
Aug 15, 2003·Health Policy and Planning·Trudy HarphamMagna Aidoo
Jun 1, 1961·Archives of General Psychiatry·A T BECKJ ERBAUGH
Nov 29, 2005·European Archives of Psychiatry and Clinical Neuroscience·Robert F AndaWayne H Giles
Sep 8, 2006·Journal of Trauma & Dissociation : the Official Journal of the International Society for the Study of Dissociation (ISSD)·Cherie L VillanoJoyce Wallace
Nov 28, 2006·Bulletin of the World Health Organization·T VosK Webster
Jan 16, 2007·Lancet·Susan P WalkerUNKNOWN International Child Development Steering Group
Jul 4, 2008·The New England Journal of Medicine·Peter D GluckmanKent L Thornburg
May 6, 2010·Proceedings of the National Academy of Sciences of the United States of America·Shelley E Taylor
Jul 9, 2010·Journal of the American Academy of Child and Adolescent Psychiatry·Alice S CarterMargaret J Briggs-Gowan
Jul 21, 2010·Pediatrics·Roseriet BeijersCarolina de Weerth
Aug 28, 2010·Journal of Paediatrics and Child Health·Stefania MaggiClyde Hertzman
Oct 1, 2010·Developmental Psychobiology·Christine HeimCharles B Nemeroff
May 4, 2011·Reproductive Health·Mary HartleyMary Jane Rotheram-Borus
Jun 23, 2011·BJOG : an International Journal of Obstetrics and Gynaecology·C FlachL M Howard
Feb 3, 2012·BMC Pediatrics·Daynia E BallotPeter A Cooper
Mar 13, 2012·Child Psychiatry and Human Development·Dawn KingstonHeather Whitfield
Nov 3, 2012·South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde·Bavanisha VythilingumDan J Stein
Mar 12, 2013·Prevention Science : the Official Journal of the Society for Prevention Research·Mark TomlinsonMary Jane Rotheram-Borus
Apr 19, 2013·African Journal of Psychiatry·A RoosD J Stein
Nov 21, 2013·American Journal of Respiratory and Critical Care Medicine·Elysia M HollamsPeter D Sly
Jan 17, 2014·The Lancet. Respiratory Medicine·Janet StocksSamatha Sonnappa
Mar 19, 2014·Advances in Preventive Medicine·Petal Petersen WilliamsCharles D H Parry
Dec 31, 2014·Pediatrics·Tina L ChengUNKNOWN Committee on Pediatric Research

❮ Previous
Next ❯

Citations

Jan 5, 2016·Alcoholism, Clinical and Experimental Research·Kirsten A DonaldDan J Stein
Jul 21, 2016·Philosophy, Ethics, and Humanities in Medicine : PEHM·Whitney BarnettDan J Stein
Aug 11, 2016·American Journal of Respiratory and Critical Care Medicine·Diane M GrayHeather J Zar
Nov 20, 2016·Thorax·Diane GrayHeather J Zar
Sep 19, 2018·Current Behavioral Neuroscience Reports·John R PfeifferMonica Uddin
Jan 13, 2015·Respirology : Official Journal of the Asian Pacific Society of Respirology·Diane GrayZoltán Hantos
Nov 22, 2019·PloS One·Heather J ZarDan J Stein
Jun 13, 2019·Nature Communications·Darina CzamaraElisabeth B Binder
Oct 3, 2020·Nature Reviews. Nephrology·Mignon McCullochWilliam E Smoyer
Dec 3, 2017·Alcoholism, Clinical and Experimental Research·Bronwyn MyersDan J Stein
Apr 20, 2020·Brain Imaging and Behavior·Annerine RoosKirsten A Donald
Oct 24, 2018·Current Psychiatry Reports·Laramie E DuncanHanyang Shen
Jan 9, 2021·Molecular Psychiatry·Sara SammallahtiJari Lahti
Apr 2, 2021·Archives of Women's Mental Health·Karen T MaréDan J Stein
Jun 29, 2021·Drug and Alcohol Dependence·Annerine RoosKirsten A Donald
Jul 20, 2021·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Lee M GintonDan J Stein
Jul 9, 2017·Paediatric Respiratory Reviews·Heather J Zar
Nov 10, 2021·Translational Psychiatry·Emily DrzymallaAnke Hüls

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.