Investigation into optimal treatment intervals of facial port-wine stains using the pulsed dye laser

Journal of the American Academy of Dermatology
Robert AnolikR G Geronemus

Abstract

Port-wine stains (PWS) affect 0.3% to 0.5% of newborns and pulsed dye laser (PDL) remains the treatment of choice. Optimal treatment intervals have not been established. We sought to validate the optimal treatment intervals for the management of facial PWS with PDL. In all, 24 infants with facial PWS who received at least 5 treatments with the PDL at 2-, 3-, and 4-week intervals at a private laser and skin surgery center from 2009 to 2010 were identified by a retrospective chart review. Safety and efficacy were compared by blinded investigators. Side effects were equivalent in all interval groups and included only expected short-term erythema, edema, purpura, and mild postinflammatory hyperpigmentation. No patient developed hypopigmentation, scarring, or infection. All interval groups showed 50% to 100% clearance of their PWS after 5 treatments. Complete or near-complete clearance was seen in 6 of 8 (75%) and 7 of 8 (87.5%) patients in the 2- and 3-week interval groups, respectively, as compared with 3 of 8 (37.5%) patients in the 4-week interval group. This was a retrospective chart review from a single institution. Long-term side effects and recurrence rates were not assessed. We conclude that PDL treatments at 2-, 3-, and 4-...Continue Reading

References

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Citations

Feb 24, 2016·Clinics in Dermatology·Karen A Chernoff, Julie V Schaffer
May 2, 2015·Journal of the European Academy of Dermatology and Venereology : JEADV·M AdamičP Boixeda
Sep 23, 2016·Journal of the European Academy of Dermatology and Venereology : JEADV·D L PerruchoudM A Adatto
Mar 26, 2019·Journal of the European Academy of Dermatology and Venereology : JEADV·M I van RaathM Heger
Dec 29, 2020·Pediatric Dermatology·Jennifer M TranLisa M Arkin
Aug 3, 2021·Dermatologic Therapy·Andrea EstébanezJose María Martín Hernández

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