Investigation into the acute effects of total and partial energy restriction on postprandial metabolism among overweight/obese participants

The British Journal of Nutrition
Rona AntoniM Denise Robertson

Abstract

The intermittent energy restriction (IER) approach to weight loss involves short periods of substantial (75-100 %) energy restriction (ER) interspersed with normal eating. This study aimed to characterise the early metabolic response to these varying degrees of ER, which occurs acutely and prior to weight loss. Ten (three female) healthy, overweight/obese participants (36 (SEM 5) years; 29·0 (sem 1·1) kg/m2) took part in this acute three-way cross-over study. Participants completed three 1-d dietary interventions in a randomised order with a 1-week washout period: isoenergetic intake, partial 75 % ER and total 100 % ER. Fasting and postprandial (6-h) metabolic responses to a liquid test meal were assessed the following morning via serial blood sampling and indirect calorimetry. Food intake was also recorded for two subsequent days of ad libitum intake. Relative to the isoenergetic control, postprandial glucose responses were increased following total ER (+142 %; P=0·015) and to a lesser extent after partial ER (+76 %; P=0·051). There was also a delay in the glucose time to peak after total ER only (P=0·024). Both total and partial ER interventions produced comparable reductions in postprandial TAG responses (-75 and -59 %, resp...Continue Reading

References

May 1, 1990·Metabolism: Clinical and Experimental·P I Mansell, I A Macdonald
Feb 1, 1988·Diabetes/metabolism Reviews·M McMahonR Rizza
Oct 1, 1987·The American Journal of Clinical Nutrition·K S NairD E Matthews
Nov 1, 1986·The American Journal of Clinical Nutrition·J O de BoerJ G Hautvast
Jan 1, 1972·The American Journal of Clinical Nutrition·J W Anderson, R H Herman
Mar 1, 1994·The British Journal of Nutrition·J Webber, I A Macdonald
Jun 15, 1996·The Journal of Clinical Investigation·M RodenG I Shulman
Feb 1, 1996·Physiological Measurement·M J NicholsonI T Campbell
Sep 12, 2001·American Journal of Physiology. Endocrinology and Metabolism·M D JensenB R Landau
Nov 10, 2001·American Journal of Physiology. Endocrinology and Metabolism·B MittendorferS Klein
Dec 4, 2002·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·A M JohnstoneR J Stubbs
Oct 4, 2003·Current Atherosclerosis Reports·Dianne HysonLars Berglund
Apr 19, 2005·Obesity Research·Leonie K HeilbronnEric Ravussin
May 25, 2006·Journal of the American Dietetic Association·Charlene CompherUNKNOWN Evidence Analysis Working Group
Aug 9, 2007·American Journal of Physiology. Endocrinology and Metabolism·Bryan C BergmanDaniel H Bessesen
Jun 1, 2005·Nutrition Research Reviews·F BrounsT M S Wolever
Dec 25, 2008·American Journal of Physiology. Endocrinology and Metabolism·B SalginD B Dunger
May 1, 2009·Cardiovascular Diabetology·Koichi Node, Teruo Inoue
Jan 5, 2010·Physiology & Behavior·David A Levitsky, Lisa DeRosimo
Oct 6, 2010·International Journal of Obesity : Journal of the International Association for the Study of Obesity·M N HarvieA Howell
Oct 18, 2012·American Journal of Physiology. Endocrinology and Metabolism·Maarten R SoetersJohannes A Romijn
Jul 26, 2014·Journal of Nutrition and Metabolism·Eric P Plaisance, Gordon Fisher

❮ Previous
Next ❯

Citations

Jan 17, 2017·The Proceedings of the Nutrition Society·Rona AntoniM Denise Robertson
Oct 4, 2017·Nutrition Reviews·Ben van OmmenSuzan Wopereis
Nov 8, 2018·The British Journal of Nutrition·David J ClaytonLewis J James
Mar 7, 2017·Frontiers in Behavioral Neuroscience·Jean-Pascal MorinGustavo Pacheco-López
Jan 19, 2019·Sports·Jackson James PeosPaul Fournier
Jun 14, 2020·International Journal of Environmental Research and Public Health·Przemysław DomaszewskiEwa Sadowska-Krępa
Jul 24, 2020·Indian Journal of Endocrinology and Metabolism·Pratap SancheteeM K Garg
Apr 28, 2018·Current Obesity Reports·Mary-Catherine StockmanCaroline M Apovian
Mar 3, 2020·Journal of Nutritional Science and Vitaminology·Mi-Young ParkKiwon Lim
Jun 19, 2020·Journal of Diabetes and Metabolic Disorders·Inass ShaltoutMazen Ahmed Attia
May 1, 2019·Journal of Lipid and Atherosclerosis·Gwangho Yoon, Juhyun Song
Jul 19, 2017·Annual Review of Nutrition·Ruth E Patterson, Dorothy D Sears
Jun 6, 2018·International Journal of Environmental Research and Public Health·Michelle L HeadlandJennifer B Keogh
Jul 23, 2020·The British Journal of Nutrition·Julia K Zakrzewski-FruerJohn Hough
Jan 30, 2021·The Cochrane Database of Systematic Reviews·Mohammed AllafAbbas Dehghan
Mar 28, 2021·Current Atherosclerosis Reports·Kelsey GabelKrista A Varady
Aug 6, 2021·Experimental Gerontology·Xiao Tong Teong, Leonie K Heilbronn
Oct 12, 2021·Annual Review of Nutrition·Krista A VaradyKelsey Gabel

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.