Investigation of an SFOV hybrid gamma camera for thyroid imaging

Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)
S L BugbyA C Perkins

Abstract

The Hybrid Compact Gamma Camera (HCGC) is a small field of view (SFOV) portable hybrid gamma-optical camera intended for small organ imaging at the patient bedside. In this study, a thyroid phantom was used to determine the suitability of the HCGC for clinical thyroid imaging through comparison with large field of view (LFOV) system performance. A direct comparison with LFOV contrast performance showed that the lower sensitivity of the HCGC had a detrimental effect on image quality. Despite this, the contrast of HCGC images exceeded those of the LFOV cameras for some image features particularly when a high-resolution pinhole collimator was used. A clinical simulation showed that thyroid morphology was visible in a 5 min integrated image acquisition with an expected dependency on the activity within the thyroid. The first clinical use of the HCGC for imaging thyroid uptake of (123)I is also presented. Measurements indicate that the HCGC has promising utility in thyroid imaging, particularly as its small size allows it to be brought into closer proximity with a patient. Future development of the energy response of the HCGC is expected to further improve image detectability.

References

Jan 24, 2003·European Journal of Nuclear Medicine and Molecular Imaging·Cherry A Zervas, Lyda Gogou
Jul 17, 2009·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Alain Seret
Jun 8, 2012·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Makoto Tsuchimochi, Kazuhide Hayama
Nov 15, 2013·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·S L BugbyA C Perkins
Dec 3, 2014·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·B S BhatiaA C Perkins
May 22, 2016·Clinical Radiology·UNKNOWN The Royal College Of RadiologistsUNKNOWN Administration Of Radioactive Substances Advisory Committee

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Citations

Mar 12, 2017·Sensors·John E LeesAlan C Perkins
Jul 10, 2019·Expert Review of Medical Devices·Matthias N Van OosteromFijs W B Van Leeuwen
Jan 18, 2018·The British Journal of Surgery·M A StammesJ S D Mieog
Aug 15, 2017·Clinical and Translational Imaging : Reviews in Nuclear Medicine and Molecular Imaging·S L BugbyA C Perkins

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