PMID: 9430345Jun 1, 1997Paper

Investigation of BOLD contrast in fMRI using multi-shot EPI

NMR in Biomedicine
R S MenonJ S Gati

Abstract

High resolution volume coverage of the brain in fMRI studies can be accomplished using multi-slice, multi-shot EPI. We demonstrate that the optimum contrast sensitivity in BOLD based fMRI experiments using multi-shot EPI is achieved by using the shortest possible TR values between segments and the longest tolerable echo train length. For a fixed paradigm time, acquiring the largest number of images under these conditions yields the best statistical detection thresholds. For a multi-slice multi-shot EPI fMRI study, the best approach is to perform the acquisition of all the segments in a single slice before continuing on to each of the slices in turn. Our results regarding the number of shots and TR are also applicable to other multi-shot techniques such as interleaved spirals.

References

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Citations

Mar 18, 1999·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·R S Menon, B G Goodyear
Aug 14, 1998·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·C G Thomas, R S Menon
Jan 22, 2002·Trends in Neurosciences·Owen J Arthurs, Simon Boniface
Jun 20, 2003·NeuroImage·Christine PreibischHeinrich Lanfermann
Jun 25, 2003·Investigative Radiology·Richard FrayneRobert J Sevick
Dec 11, 2013·Magnetic Resonance Imaging·Xiaomu SongPooja Gaur
Jun 25, 2010·Magnetic Resonance Imaging·Paul E SummersCarlo A Porro
Oct 17, 2015·Journal of Neuroscience Methods·Xiaomu SongNan-kuei Chen
May 30, 2006·Neuroimaging Clinics of North America·Henning U VossBruce D McCandliss
Apr 24, 2009·Human Brain Mapping·Andrew S KayserMark D'Esposito
May 30, 2015·International Journal of Imaging Systems and Technology·Xiaomu SongNan-Kuei Chen
Sep 10, 1999·Journal of Magnetic Resonance·C Preibisch, A Haase
May 2, 2006·Journal of Magnetic Resonance Imaging : JMRI·Stefan Sunaert
Jul 25, 2020·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Avery J L BermanJonathan R Polimeni
Aug 21, 2019·Frontiers in Systems Neuroscience·Praveen KulkarniCraig F Ferris
Feb 4, 2021·Animal Models and Experimental Medicine·Christopher M LawsonCraig F Ferris
Feb 25, 2021·Biological Psychiatry : Cognitive Neuroscience and Neuroimaging·Ilayda AlkislarCraig F Ferris

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