Investigation of dispersion effects in ocular media by multiple wavelength partial coherence interferometry

Experimental Eye Research
W DrexlerA F Fercher

Abstract

We report on quantitative measurements of group refractive indices and group dispersion in water and in human ocular media such as the cornea, the aqueous humor, the lens, artificial intraocular lenses, as well as a total value averaged over the media along the axial eye length of normal subjects and pseudophakic patients in vivo using dual beam partial coherence interferometry. Different optical thickness values due to the dispersion of the cornea are demonstrated using two spectrally displaced light sources. The displacement can be used to indirectly calculate the group dispersion of the human cornea in the spectral region between 810 nm and 860 nm. If the object under investigation is dispersive, resolution is limited due to a broadening of the detected signals. This broadening increases with group dispersion, i.e., the extent to which the group refractive index of the medium varies with wavelength and thickness of the tissue under investigation as well as with the spectral bandwidth of the light source. Measurements of the group dispersion in the cornea, lens and vitreous of pseudophakic and normal human eyes, show that the cornea and the lens are more dispersive than water-by a factor of about 5 and 2, respectively-in the ...Continue Reading

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Citations

Jul 26, 2003·The British Journal of Ophthalmology·H Eleftheriadis
Sep 18, 2007·Journal of Biomedical Optics·Felix SpölerNorbert F Schrage
Aug 28, 1998·Journal of Cataract and Refractive Surgery·O FindlA F Fercher
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