Investigation of dynamic deformation of the midbrain in rear-end collision using human brain FE model

Computer Methods in Biomechanics and Biomedical Engineering
Noritoshi AtsumiJun Shinoda

Abstract

Mild traumatic brain injury (TBI), including concussions, can cause symptoms affecting physical or cognitive domains in the acute and chronic phases. In this study, we investigated the dynamic deformation of the brain stem, which might be important for these symptoms, using a human brain finite element model through reconstruction simulations of rear-end collisions in three different velocities. In all simulations, high maximum principal strain values were observed at the midbrain that were higher than those in the corpus callosum. These findings could provide some mechanical insights into brain disorders associated with mild TBI.

References

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Feb 7, 2018·Annals of Biomedical Engineering·Noritoshi AtsumiMasami Iwamoto
Aug 29, 2019·Science Advances·Adnan A HiradBradford Z Mahon

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Software Mentioned

LS
DYNA
THUMS

Related Concepts

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Brain Injury & Trauma

brain injury after impact to the head is due to both immediate mechanical effects and delayed responses of neural tissues.

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