Investigation of killer cell immunoglobulin-like receptor gene diversity: II. KIR2DS4

Human Immunology
L D MaxwellD Middleton

Abstract

A polymerase chain reaction sequence-specific oligonucleotide probe typing method identifying and distinguishing alleles of the KIR2DS4 gene has been established. The system is based on the specific amplification of a region of this gene, followed by hybridization with 11 sequence-specific oligonucleotide probes. The method has been applied to a healthy group of Northern Irish caucasian individuals, establishing frequencies of alleles of this locus within the local population. Furthermore, cell line DNA and families from the 13th International Histocompatibility Workshop, in addition to local families, have also been allele typed at the KIR2DS4 locus. Haplotype segregation, with respect to KIR2DS4 alleles, has been examined by using the local family data. Within all sample groups investigated, four KIR2DS4 alleles were identified, two of which are novel to this investigation.

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Citations

Jan 4, 2007·Immunogenetics·D MiddletonP A Gourraud
Jun 15, 2014·Human Immunology·Subulade A OlaniyanOlayemi O Omotade
May 23, 2006·International Journal of Immunogenetics·W LuszczekP Kuśnierczyk
May 15, 2007·Tissue Antigens·A C FloresL Fainboim
Dec 24, 2009·Immunology·Derek Middleton, Faviel Gonzelez
Mar 25, 2014·Journal of Clinical Laboratory Analysis·Amanda Vansan MarangonAna Maria Sell
Feb 8, 2005·Human Immunology·Dong Hee WhangMyoung Hee Park
Jul 11, 2009·Human Immunology·Asensio GonzalezDerek Middleton
Jun 29, 2005·Transplant Immunology·Derek MiddletonIris A Halfpenny
Jul 15, 2015·Journal of Translational Medicine·Qiongxiu ZhouFeng Ma
Nov 19, 2013·Clinical Immunology : the Official Journal of the Clinical Immunology Society·Heather A HongCaroline T Tiemessen
Feb 1, 2018·International Journal of Hematology·Rohtesh S MehtaKatayoun Rezvani
Jun 6, 2017·Frontiers in Immunology·Bercelin ManiangouKatia Gagne
Oct 6, 2020·Frontiers in Immunology·Jesse BruijnesteijnRonald E Bontrop
Aug 30, 2011·Journal of Leukocyte Biology·Olympe ChazaraAshley Moffett

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