Investigation of the candidate genes ACTHR and golf for bipolar illness by the transmission/disequilibrium test

Genetic Epidemiology
H BickeböllerM Scholz

Abstract

Several versions of the transmission/disequilibrium test (TDT) were applied to the two candidate genes ACTHR and Golf for bipolar illness. Analyses were carried out separately for paternal and maternal transmission. Evidence for linkage and association was found for ACTHR for paternal transmission in support of a parent-of-origin effect. Possible evidence for segregation distortion was found for one of the two markers for Golf for maternal transmission.

References

Jul 1, 1995·Annals of Human Genetics·P C Sham, D Curtis
Jun 21, 1994·Proceedings of the National Academy of Sciences of the United States of America·W H BerrettiniE S Gershon
May 31, 1996·American Journal of Medical Genetics·N B FreimerL A Sandkuijl

❮ Previous
Next ❯

Citations

Sep 12, 2008·Biological Reviews of the Cambridge Philosophical Society·Bernard Crespi
Nov 30, 2011·Epigenomics·Kristin D Kernohan, Nathalie G Bérubé
Mar 20, 2002·Psychiatric Genetics·Peter ZillBrigitta Bondy

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bipolar Disorder

Bipolar disorder is characterized by manic and/or depressive episodes and associated with uncommon shifts in mood, activity levels, and energy. Discover the latest research this illness here.