Investigation of the Utility and Safety of Dynamic Computed Tomography with Vasodilators

Yonago Acta Medica
Jun WatanabeMasahide Ikeguchi

Abstract

Dynamic computed tomography (CT) angiography is useful for evaluating of hepatic vascularity. Although vasodilators increase hepatic blood flow, the utility of dynamic CT with vasodilators is unclear. Here we investigated the utility and safety of dynamic CT with vasodilators. A prospective case-control radiographic evaluation using abdominal dynamic CT with and without vasodilator was performed at a single center between October 2015 and September 2016. We compared the CT values in Hounsfield units of the aorta; celiac artery; and common, right, and left hepatic arteries in the arterial phase and the main trunk; right and left branches of the portal vein; and right, middle, and left hepatic veins in the portal phase with and without vasodilators. The region of interest was set in each element of the liver vasculature. Four radiological technologists independently and visually compared the scores of the portal vein (P-score) and hepatic vein (V-score) on a 5-point scale with and without vasodilators. The CT values of arteries and veins using vasodilators were significantly higher than those without vasodilators. With and without vasodilators, the P-scores were 3.1 ± 1.2 and 4.0 ± 1.1 (P < 0.05) and the V-scores were 3.3 ± 1.4 a...Continue Reading

References

Nov 1, 1982·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·R J GroszmannE H Storer
Oct 26, 2005·The Journal of Surgical Research·Shouho HayashiMorito Monden
Jul 20, 2017·Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes·Kathleen Eddy, Andreu F Costa
Apr 10, 2018·Journal of Hepatology·UNKNOWN European Association for the Study of the Liver. Electronic address: easloffice@easloffice.eu, UNKNOWN European Association for the Study of the Liver

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