Investigation of the XCAT phantom as a validation tool in cardiac MRI tracking algorithms

Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)
N J LowtherP J Keall

Abstract

To describe our magnetic resonance imaging (MRI) simulated implementation of the 4D digital extended cardio torso (XCAT) phantom to validate our previously developed cardiac tracking techniques. Real-time tracking will play an important role in the non-invasive treatment of atrial fibrillation with MRI-guided radiosurgery. In addition, to show how quantifiable measures of tracking accuracy and patient-specific physiology could influence MRI tracking algorithm design. Twenty virtual patients were subjected to simulated MRI scans that closely model the proposed real-world scenario to allow verification of the tracking technique's algorithm. The generated phantoms provide ground-truth motions which were compared to the target motions output from our tracking algorithm. The patient-specific tracking error, ep, was the 3D difference (vector length) between the ground-truth and algorithm trajectories. The tracking errors of two combinations of new tracking algorithm functions that were anticipated to improve tracking accuracy were studied. Additionally, the correlation of key physiological parameters with tracking accuracy was investigated. Our original cardiac tracking algorithm resulted in a mean tracking error of 3.7 ± 0.6 mm over...Continue Reading

Citations

Apr 20, 2020·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Oliver BlanckHendrik Bonnemeier
Nov 8, 2020·International Journal of Radiation Oncology, Biology, Physics·Suzanne Lydiard PGDipPaul Keall
Jul 28, 2021·Physics in Medicine and Biology·Nicholas HindleyPaul Keall

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