PMID: 11934502Apr 6, 2002Paper

Investigation of the yvgW Bacillus subtilis chromosomal gene involved in Cd(2+) ion resistance

FEMS Microbiology Letters
Irina M Solovieva, K D Entian

Abstract

Analysis of the complete genome sequence of Bacillus subtilis has identified the gene yvgW encoding a protein of 703 amino acids with sequence similarity to the cadmium resistance determinant CadA from the Staphylococcus aureus plasmid pI258. Deletion of yvgW (designated cadA) resulted in increased sensitivity of the strain to cadmium. The cadA gene is expressed from its own promoter, and its expression is induced by cadmium. Northern hybridization analysis showed that cadmium induces the synthesis of a 2.2-kb cadA transcript. These results indicate that cadA is the chromosomal determinant to cadmium resistance in B. subtilis.

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Citations

Apr 2, 2005·Current Opinion in Microbiology·Charles M Moore, John D Helmann
Mar 20, 2003·FEMS Microbiology Letters·David S RadfordJennifer S Cavet
Dec 31, 2008·Applied and Environmental Microbiology·Jessica C WilksJoan L Slonczewski
Mar 6, 2003·Journal of Bacteriology·Lars Ingo Ole LeichertMichael Hecker
May 23, 2008·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Margaret A KihlkenNick E Le Brun
Sep 13, 2014·Molecular Microbiology·Zhen MaJohn D Helmann
Jun 28, 2003·FEMS Microbiology Reviews·Dietrich H Nies
Jun 14, 2005·Molecular Microbiology·Charles M MooreJohn D Helmann
Aug 28, 2021·Microorganisms·Badriyah Shadid AlotaibiSaba Shamim

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