Mar 17, 2018

Investigations of Photosensitive Proteins by Serial Crystallography

Biochemistry. Biokhimii︠a︡
G K SelikhanovA G Gabdulkhakov

Abstract

This review contains recent data on serial femtosecond X-ray crystallography (SFX), based on a femtosecond X-ray free electron laser, as well as, on the possibilities of its application for studying photosensitive proteins. Development of this method began rather recently, and it has already shown its effectiveness and some unique advantages over conventional X-ray structural analysis. This technology is especially promising for structural studies of membrane proteins and for kinetic studies. The main principle of the method, the possibility of its application in structural biology, its advantages and disadvantages, as well as its prospects for further development are analyzed in this review. Special attention is given to publications in which the SFX method has been used to study photosensitive proteins.

  • References64
  • Citations1

References

  • References64
  • Citations1

Citations

Mentioned in this Paper

Study
Plain X-ray
Crystallography, X-Ray
Evaluation
6-(fluorescein-5-carboxamido)hexanoic acid succimidyl ester
Radiographic Imaging Procedure
Membrane Proteins
Analysis
Attention
Photosensitizing Agents

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