Investigations on the biology, epidemiology, pathology and control of Tunga penetrans in Brazil: IV. Clinical and histopathology

Parasitology Research
Hermann FeldmeierJorg Heukelbach

Abstract

Tungiasis is a parasitic skin disease caused by the sand flea Tunga penetrans. This ectoparasitosis is endemic in South America, the Caribbean and sub-Saharan Africa, where it is an important but neglected health problem in resource-poor communities. As part of a study of tungiasis-related morbidity in a typical slum in Fortaleza, Brazil, we identified 86 individuals with tungiasis. Lesions were counted, classified according to the stage of development, and clinical pathology was documented. One hundred and nine lesions were biopsied and examined by histological sectioning. The patients had between 1 and 145 lesions (median 14.5), the majority occurring in clusters. In all, 77% of patients reported severe pain at the site of the lesion, and 52% had one or more nails lost or severely deformed. Intense inflammation and/or fissures hindered 45% of the patients from walking normally. Signs of superinfection were observed in 29%, and signs of generalized inflammation in 2% of patients. Clinical pathology was significantly related to the number of lesions, and the total number of parasites present correlated with the number of fleas occurring in clusters. Clinical pathology was frequently accompanied by a pathological alteration of t...Continue Reading

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Citations

Oct 4, 2012·Travel Medicine and Infectious Disease·M Grupper, I Potasman
Sep 27, 2005·Transactions of the Royal Society of Tropical Medicine and Hygiene·J HeukelbachH Feldmeier
Feb 7, 2012·Transactions of the Royal Society of Tropical Medicine and Hygiene·H D MazigoJ Heukelbach
Oct 23, 2008·PLoS Neglected Tropical Diseases·Daniel PilgerHermann Feldmeier
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Jun 4, 2010·The American Journal of Tropical Medicine and Hygiene·Vicente MacoEduardo Gotuzzo
Aug 22, 2014·Parasitology Research·Pedro Marcos Linardi, Daniel Moreira de Avelar
Jun 26, 2013·Parasitology Research·Pedro Marcos LinardiElias Jorge Facury Filho
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Oct 4, 2007·International Journal of Dermatology·Stefano Veraldi, Marta Valsecchi
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Jan 9, 2018·PLoS Neglected Tropical Diseases·Susanne WieseHermann Feldmeier
Jan 12, 2019·Journal of Cutaneous Pathology·Gianluca NazzaroStefano Veraldi
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Apr 6, 2021·Parasitology Research·Francis MutebiGeorg von Samsom-Himmelstjerna
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