PMID: 2167140Aug 15, 1990Paper

Investigations on the significance of the adenoma-carcinoma sequence in the small bowel

Cancer
F Sellner

Abstract

In view of the rarity of small-bowel epithelial neoplasms as compared with the case for the large bowel, evidence for an adenoma-carcinoma sequence in the small bowel was studied based on a search for data in the medical literature for the years 1927 through 1986. Sufficiently defined data were found for comparison of 185 benign adenomas, 76 adenoma-with-carcinomas, and 1333 carcinomas in patients without familial polyposis disease and for 63, five, and 30, respectively, in patients with disease. For patients without polyposis, it was found that (1) 29.8% of all small-bowel adenomas (33.6% if those at Vater's ampulla are excluded) showed malignancy; (2) the mean and median ages were lower for benign adenoma than for adenoma-with-carcinoma and carcinoma, although the ratios by sex were the same; (3) there is a nearly identical spatial distribution of the three types of epithelial neoplasms within the small bowel; and (4) both the frequency of finding adenomatous residues existing in continuity with carcinoma and the life history of the adenoma-carcinoma sequence are similar in the small bowel as in the large. In comparing these results with those from patients with familial polyposis disease, it was particularly noted that (1) t...Continue Reading

References

Nov 1, 1975·Langenbecks Archiv für Chirurgie·K SpohnK Hahn
Apr 1, 1977·Archives of Surgery·O E AkwariA H Baggenstoss
Apr 1, 1978·The Australian and New Zealand Journal of Surgery·G V Shead, M Mathan
Apr 1, 1977·Cancer·I A SpiraW I Wolff
Mar 1, 1979·Current Problems in Cancer·P J GarvinV L Willman
Feb 1, 1979·Annals of Surgery·J F Forrest, W P Longmire
Aug 1, 1979·Annals of Surgery·R P KerremansF M Penninckx
Nov 1, 1979·Gastrointestinal Endoscopy·M TaxierA Cooperman
Dec 1, 1977·Annals of Surgery·T CoutsoftidesH R Shibata
Mar 1, 1978·Archives of Surgery·P C Freeny, T R Vimont
May 1, 1978·Diseases of the Colon and Rectum·A A Keshgegian, H T Enterline
Jun 1, 1978·American Journal of Surgery·H FreundA L Durst
Jun 1, 1978·American Journal of Surgery·W SchlippertJ Christensen
Feb 23, 1978·Gastrointestinal Radiology·P C Hessler, E Braunstein
May 1, 1977·Annals of Surgery·T R Jones, F C Nance
Jul 1, 1977·Cancer Letters·A B Lowenfels, A Sonni
Sep 1, 1977·American Journal of Surgery·D F Morgan, R W Busuttil
Nov 1, 1977·Annals of Surgery·T SatoS Matsuno
Jul 1, 1976·American Journal of Surgery·M F SchultenJ M Beal
Nov 1, 1976·American Journal of Surgery·K OhmoriK Satake
Nov 1, 1976·Gastrointestinal Endoscopy·V UppaputhangkuleE A Gelzayd
Jun 1, 1975·The American Journal of Digestive Diseases·A Wald, F D Milligan
Feb 1, 1975·Annals of Surgery·N D KutinS A Localio
May 1, 1975·Annals of Surgery·K W WarrenM Relihan
May 1, 1975·The British Journal of Surgery·B Leppard, H J Bussey
Dec 1, 1975·Cancer·T MutoB C Morson
Dec 1, 1975·American Journal of Surgery·T A Treadwell, R R White
Jan 1, 1985·Langenbecks Archiv für Chirurgie·M ClemensH Bünte
Nov 1, 1987·Annals of Surgery·D H HayesJ C Bowen
Feb 1, 1988·Histopathology·I C TalbotD Carr-Locke
Oct 1, 1986·Cancer·J RosenbergP Trowbridge
Feb 1, 1986·Gastroenterology·J B Weiss, G G Semerdjian
Jan 1, 1986·The British Journal of Surgery·R A Knox, R D Kingston
Mar 1, 1986·Annals of Surgery·D P RyanA L Warshaw
Jan 1, 1985·The British Journal of Surgery·U HaglundO Rehnberg
Feb 1, 1985·Diseases of the Colon and Rectum·S BülowJ O Søndergaard
Nov 1, 1985·Diseases of the Colon and Rectum·S NakaharaK Ohsato
Sep 1, 1985·Diseases of the Colon and Rectum·F TonelliP Romagnoli
Mar 1, 1971·American Journal of Surgery·J L Ponka, N S Uthappa

❮ Previous
Next ❯

Citations

Jul 2, 1999·International Journal of Cancer. Journal International Du Cancer·E NegriS Franceschi
Jan 1, 1996·Digestive Diseases and Sciences·T SutterP R Holt
Feb 1, 1993·In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association·W H ThorntonR S MacDonald
Apr 22, 2003·Pathology Oncology Research : POR·Gábor ElekAkos Pap
Jan 26, 2005·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·J KöningerM W Büchler
Sep 1, 2005·Cancer Causes & Control : CCC·Tmirah HaselkornDavid E Lilienfeld
Jan 16, 2014·The Indian Journal of Surgery·Philip UmmanChanchal Narayan
Dec 2, 2008·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Daniel BaumhoerLuigi M Terracciano
Jul 31, 2013·Nature Reviews. Clinical Oncology·Kanwal Raghav, Michael J Overman
Jul 17, 1998·The British Journal of Surgery·M H Wallace, R K Phillips
Nov 11, 2008·Japanese Journal of Clinical Oncology·Sook Hee HongSuk Kyun Chang
Oct 6, 2001·Journal of Clinical Gastroenterology·S S GillA A Mihas
Oct 18, 2003·Journal of Clinical Gastroenterology·Shiro OkaKazuaki Chayama
Oct 7, 2003·American Journal of Clinical Oncology·Irena GusakovaSamuel Ariad
Aug 24, 2005·Inflammatory Bowel Diseases·Vanessa Palascak-JuifFranck Carbonnel
Jun 17, 2005·The American Journal of Surgical Pathology·Zong-Ming E ChenHanlin L Wang
May 21, 2010·Current Opinion in Oncology·Giovanna SperanzaShivaani Kummar
Aug 2, 2008·The American Journal of Surgical Pathology·Patrick L WagnerRhonda K Yantiss
Sep 1, 1993·Gut·K P NugentR K Phillips
Jul 17, 2003·Gut·S D RampertabP H R Green
Jun 1, 1995·Postgraduate Medical Journal·O A AdedejiM Garcia-Zarco
Nov 18, 2008·Cancer Research·Amanda J CrossArthur Schatzkin
Feb 2, 2008·World Journal of Surgical Oncology·Kongkrit ChaiyasateVijay K Mittal
Dec 22, 2011·Annals of Surgical Oncology·Michael J OvermanGeorge J Chang
Apr 5, 2011·World Journal of Gastrointestinal Oncology·Sai Yi Pan, Howard Morrison
Jun 1, 2000·Scandinavian Journal of Gastroenterology·G H SakorafasC G Dervenis
May 8, 2010·Expert Opinion on Pharmacotherapy·Guru Trikudanathan, Constantin A Dasanu
May 7, 2013·Gastrointestinal Endoscopy·Kenneth F BinmoellerSteve D Kane
Mar 19, 2013·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Elham KharazmiKari Hemminki
Oct 1, 1994·International Journal of Cancer. Journal International Du Cancer·A ScarpaR S Accolla
Oct 2, 2012·Gastrointestinal Endoscopy·Massimo ConioPeter D Siersema
Jun 19, 2012·Best Practice & Research. Clinical Gastroenterology·Jan Jacob Koornstra
Apr 16, 2011·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·James R A SkipworthArjun Shankar
Nov 21, 2009·American Journal of Clinical Pathology·Diana M CardonaChen Liu
Mar 26, 2010·Human Pathology·Hee-Kyung ChangUNKNOWN Korean Small Intestinal Cancer Study Group
Sep 1, 2015·Critical Reviews in Oncology/hematology·Matthias BarralPhilippe Soyer
Aug 4, 2009·Gastrointestinal Endoscopy Clinics of North America·Stijn J B Van WeyenbergJürgen Pohl
Aug 4, 2009·Gastrointestinal Endoscopy Clinics of North America·Shirley C Paski, Carol E Semrad
Dec 10, 2008·Annals of Epidemiology·David SchottenfeldFawn D Vigneau
Oct 24, 2007·American Journal of Clinical Pathology·Megan Q ZhangHanlin L Wang
Sep 2, 2008·The Lancet Oncology·Jan J KoornstraHans F A Vasen
Aug 2, 2008·The Surgical Clinics of North America·Wigdan Al-SukhniSteven Gallinger

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adenomatous Polyposis Coli

Adenomatous polyposis coli is a protein encoded by the APC gene and acts as a tumor suppressor. Discover the latest research on adenomatous polyposis coli here.