PMID: 12757944May 22, 2003Paper

Involvement of enterobactin in norepinephrine-mediated iron supply from transferrin to enterohaemorrhagic Escherichia coli

FEMS Microbiology Letters
Primrose P FreestoneMark Lyte

Abstract

Exposure of bacteria to members of the stress-associated family of catecholamine hormones, principally norepinephrine, has been demonstrated to increase both growth and production of virulence-related factors. Mutation of genes for enterobactin synthesis and uptake revealed an absolute requirement for enterobactin in norepinephrine-stimulated growth of Escherichia coli O157:H7. The autoinducer produced by norepinephrine-stimulated E. coli could not substitute for enterobactin. We also demonstrate that norepinephrine promotes iron shuttling between transferrin molecules, thereby enabling the bacterial siderophore enterobactin to more readily acquire iron for growth. These results suggest one of the possible mechanisms by which the hormonal output of stress may affect enterohaemorrhagic E. coli pathogenicity.

References

Oct 24, 1979·Biochimica Et Biophysica Acta·E H Morgan
Jan 1, 1992·Life Sciences·M Lyte, S Ernst
Jul 1, 1991·Reviews of Infectious Diseases·P K PetersonB M Sharp
Jul 26, 1968·Biochemical and Biophysical Research Communications·P Aisen
Nov 10, 1995·The Journal of Biological Chemistry·J B Neilands
Jun 1, 1993·The Journal of Endocrinology·M Lyte
Mar 27, 1997·Biochemical and Biophysical Research Communications·M LyteD H Francis
Jul 1, 1997·The Journal of Surgical Research·M Lyte, M T Bailey
Mar 18, 1999·FEMS Microbiology Letters·P P FreestoneM Lyte
Oct 6, 2000·Annual Review of Microbiology·C Ratledge, L G Dover
Feb 28, 2002·Annual Review of Immunology·Jeanette I WebsterEsther M Sternberg
Jun 5, 2002·Life Sciences·Tesfaye Belay, Gerald Sonnenfeld

❮ Previous
Next ❯

Citations

Jan 1, 2004·Trends in Microbiology·Mark Lyte
Jul 1, 2010·Animal : an International Journal of Animal Bioscience·P Freestone, M Lyte
Jan 17, 2008·Nature Reviews. Microbiology·David T Hughes, Vanessa Sperandio
May 23, 2009·British Journal of Anaesthesia·N MongardonM Singer
Jul 6, 2006·Applied and Environmental Microbiology·Phyllis M O'DonnellGerald Sonnenfeld
Apr 9, 2008·Journal of Bacteriology·Mark T Anderson, Sandra K Armstrong
Sep 11, 2012·Journal of Bacteriology·Kendra H SteeleJason W Johnston
Jan 22, 2008·Journal of Bacteriology·Claire E MillerJulian M Ketley
May 6, 2010·Journal of Leukocyte Biology·Katherine A Radek
Jan 2, 2014·Scientifica·Primrose Freestone
Jan 9, 2009·Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine·Timothy J Brickman, Sandra K Armstrong
Dec 7, 2010·Burns : Journal of the International Society for Burn Injuries·Adrienne A HammondAbdul N Hamood
Jan 15, 2008·Trends in Microbiology·Primrose P E FreestoneMark Lyte
Sep 14, 2007·International Journal of Food Microbiology·Primrose P E FreestoneMark Lyte
Dec 13, 2012·Molecular Microbiology·Michail H KaravolosC M Anjam Khan
Oct 4, 2013·Microbiology·Sara SandriniPrimrose Freestone
Sep 26, 2009·Microbiology·Pol Nadal JimenezWim J Quax
Mar 21, 2015·The Journal of Endocrinology·Sara SandriniPrimrose Freestone
Jun 30, 2012·Gut Microbes·Maha Al-AsmakhSven Pettersson
May 20, 2008·Advances in Applied Microbiology·Primrose P E Freestone, Mark Lyte
Aug 1, 2018·International Journal of Molecular Sciences·Kalina Duszka, Walter Wahli
May 28, 2019·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Marwh AldriweshPrimrose Freestone
Dec 15, 2016·Frontiers in Medicine·Douglas B Kell, Louise C Kenny

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.